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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 93 - 113 (21page)
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Objective :This study aimed to review the performance of traditional herbal prescriptions for treating dementia and present a strategy for research on dementia therapy utilizing herbal medicine.
Methods :A definition was made to clarify the technology regarding the development of herbal prescriptions for treating dementia. The queries were compounded based on the initial keywords provided by experts in the field, then applied to the Web of Science database search engines from January 1986 to September 2011 to search related scientific articles. Before performing the analysis, papers were extracted from the initial search reviewed by experts and 80 articles were selected. Then, the selected papers were analyzed in terms of publish year, country, and type of herbal prescriptions. Furthermore, the research performance evaluation for treating dementia by herbal prescriptions was also created in terms of country and organization based on forward citation analysis. In addition to, for the evaluation regarding research quality, we classified and reviewed papers into two types: clinical studies and experimental studies.
Results :According to the quantitative information analysis of 80 articles, the number of papers has increased by 21.9% per the yearly mean from 1995, and Japan had the largest portion within this research field. There were 34 kinds of traditional herbal prescriptions, among them Ukgansan had the highest number of studies followed by Jodeungsan,Dangkisoosan and so on. In addition, quality index as calculated by cites per paper is higher than average in Switzerland, Turkey and Japan. In the view of the evaluation on quality there were 12 clinical studies, 8 RCT reported that herbal prescriptions had efficacy at cognition, behavioral & psychological symptoms (BPSD) and activity of daily life (ADL) in various type of dementia. In experimental studies most of the studies were performed using animal models. The studies using Ukgansan were aimed at improving BPSD. The papers studied with Jodeungsan and Dangkisoosan targeted vascular dementia.
Conclusions :In this study, research to develop traditional herbal prescriptions for treating dementia has the potential to improve symptoms since herbal medicines work as both multi-function and multi-target in dementia with multiple pathological or neurotoxic pathways. Therefore, the results of the research should be used in order to establish strategies to develop technology for treating dementia with traditional herbal prescriptions in the future.
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참고문헌 (24)
참고문헌 신청
Fø n n ebø V / 2007 / Researching complementary and alternative treatments-the garekeepers are not at home / BMC Med Res Methodl 7 : 7 ~
Goto H / 2011 / A Chinese herbal medicine, Tokishakuyakusan, reduces the worsening of impairments and independence after stroke:A 1-year randomized, controlled trial / Evi-bas Comple an
Iwasaki K / 2004 / A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of the chinese herbal medicine "Ba Wei Di Huang Wan" in the treatment of dementia / J Am Ger
Iwasaki K / 2005 / A randomized, observer- blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms an
Iwasaki K / 2007 / A pilot study of banxia houpu tang, a traditional Chinese medicine, for reducing pneumonia risk in older adults with dementia / J Am Geriatr Soc 55 (12) :
Goto H / 2011 / A Chinese herbal medicine, Tokishakuyakusan, reduces the worsening of impairments and independence after stroke:A 1-year randomized, controlled trial / Evi-bas Comple an
Iwasaki K / 2004 / A Randomized, Double-Blind, Placebo-Controlled Clinical Trial of the chinese herbal medicine "Ba Wei Di Huang Wan" in the treatment of dementia / J Am Ger
Iwasaki K / 2005 / A randomized, observer- blind, controlled trial of the traditional Chinese medicine Yi-Gan San for improvement of behavioral and psychological symptoms an
Iwasaki K / 2007 / A pilot study of banxia houpu tang, a traditional Chinese medicine, for reducing pneumonia risk in older adults with dementia / J Am Geriatr Soc 55 (12) :
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