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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제17권 제8호
- 발행연도
- 2007.1
- 수록면
- 1,390 - 1,393 (4page)
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In this study, three of the representative EDCs, 17β-estradiol, bisphenol A, and styrene, were employed to findtheir mode of toxic actions in E. coli. To acomplish this, fourdiferent stres response genes, recA, katG, fabA, and grpEgenes, were used as a representative for DNA, oxidative,membrane, or protein damage, respectively. The expressionlevels of these four genes were quantified using a real-timeRT-PCR after challenge with three different EDCs individually.Bisphenol A and styrene caused high-level expression of recAand katG genes, respectively, whereas 17β-estradiol made nosignificant changes in expresion of any of those genes. Theseresults lead to the classification of the mode of toxic actionsof EDCs on E. coli.
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참고문헌 (24)
참고문헌 신청
/ 1991 / B. 1991. Regulation of bacterial oxidative stress genes. Annu. Rev. Gen. 25 : 315 ~ 337
Alberto, M / 2002 / Hazard identification and risk assessment of endocrine disrupting chemicals with regard to developmental effects 27 : 367 ~ 370
Barbu / 1989 / V. and F. Dautry. 1989. Northern blot normalization with a 28S rRNA oligonucleotide probe. Nucleic Acids Res. 17 : 7115 ~
Bromberg, R / 1998 / Oxygen sensitivity of heated cells of Escherichia coli O157:H7 85 : 231 ~ 237
Bustin, S. A / 2000 / Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays 25 : 169 ~ 193
Alberto, M / 2002 / Hazard identification and risk assessment of endocrine disrupting chemicals with regard to developmental effects 27 : 367 ~ 370
Barbu / 1989 / V. and F. Dautry. 1989. Northern blot normalization with a 28S rRNA oligonucleotide probe. Nucleic Acids Res. 17 : 7115 ~
Bromberg, R / 1998 / Oxygen sensitivity of heated cells of Escherichia coli O157:H7 85 : 231 ~ 237
Bustin, S. A / 2000 / Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays 25 : 169 ~ 193
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