지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 396 - 402 (7page)
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초록· 키워드
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The chemical composition, anti-porcine epidemic diarrhea virus (PEDV) activity and antimicrobial activity of Artemisia dubia essential oil were evaluated in this study. Fifty eight compounds from A. dubia essential oil were identified through analysis by gas chromatography-mass spectrometry (GC-MS). The major constituents of the oil were camphor (17.18 %), germacrene-D (15.70%), trans (β-) racaryophyllene (6.79%), ene thujones (6.57%), 1, 8-cineole (5.94%) and camphene (5.08%). The essential oil was evaluated for antiviral activity against PEDV in Vero cells using a cytopathic effect (CPE) reduction method. The oils actively inhibited PEDV replication with a 50% inhibitory concentration (IC50) of 43.7 μ3/mL. The 50% cytotoxicity concentration (CC50) of the oils was over 100 μ/mL and the derived therapeutic index was >2.3. Similar analysis of the ribavirin revealed that they have a relatively weaker efficacy when compared to the oils. The antimicrobial activity of the essential oil against 5 microorganisms was evaluated by the disc diffusion method. The essential oil exhibited antimicrobial activity against 5 tested microorganisms with a clear zone of 8-22 mm. Among the tested microorganisms, Streptococcus pyogenes was the most sensitive and Candida albicans the least.
Therefore, in can be concluded that essential oils of A. dubia may have interesting applications for microbial control or the control of PEDV-derived diseases.
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참고문헌 (24)
참고문헌 신청
Adams, R. P / 2001 / Identification of essential oils components by gas chromatography/quadrupole mass spectroscopy, Allured Publishing Corporation / Illinois
Blagojevic, P / 2006 / Chemical composition of the essential oils of serbian wild-growing Artemisia absinthium and Artemisia vulgaris / J. Agric. Food Chem 54 : 4780 ~ 4789
Burt, S. A. / 2004 / Essential oils: their antibacterial properties and potential applications in foods?a review / Int. J. Food Microbiol 94 : 223 ~ 253
Chagonda, L. S / 1999 / The essential oil of cultivated Artemisia afra (Jacq.) from Zimbabwe / Flav. Fragr. J 14 : 140 ~ 142
Chericoni, S / 2004 / GC-MS analyses of the essential oil from the aerial parts of Artemisia verlotiorum: variability during the year / Biochem. Syst. Ecol 32 : 423 ~ 429
Blagojevic, P / 2006 / Chemical composition of the essential oils of serbian wild-growing Artemisia absinthium and Artemisia vulgaris / J. Agric. Food Chem 54 : 4780 ~ 4789
Burt, S. A. / 2004 / Essential oils: their antibacterial properties and potential applications in foods?a review / Int. J. Food Microbiol 94 : 223 ~ 253
Chagonda, L. S / 1999 / The essential oil of cultivated Artemisia afra (Jacq.) from Zimbabwe / Flav. Fragr. J 14 : 140 ~ 142
Chericoni, S / 2004 / GC-MS analyses of the essential oil from the aerial parts of Artemisia verlotiorum: variability during the year / Biochem. Syst. Ecol 32 : 423 ~ 429
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