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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제25권 제5호
- 발행연도
- 2015.1
- 수록면
- 637 - 647 (11page)
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초록· 키워드
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In this study, we attempted to understand signaling pathways behind lipid biosynthesis by employing a chemical genetics approach based on small molecule inhibitors. Specific signaling inhibitors of MAP kinase or modulators of cAMP signaling were selected to evaluate the functional roles of each of the key signaling pathways in three different microalgal species: Chlamydomonas reinhardtii, Chlorella vulgaris, and Haematococcus pluvialis. Our results clearly indicate that cAMP signaling pathways are indeed positively associated with microalgal lipid biosynthesis. In contrast, MAP kinase pathways in three microalgal species are all negatively implicated in both lipid and carotenoid biosynthesis.
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참고문헌 (24)
참고문헌 신청
Alaimo PJ / 2001 / Chemical genetic approaches for the elucidation of signaling pathways / Curr. Opin. Chem. Biol 5 : 360 ~ 367
Blaby IK / 2013 / Systems-level analysis of nitrogen starvation-induced modifications of carbon metabolism in a Chlamydomonas reinhardtii starchless mutant / Plant Cell 25 :
Choi Y-E / 2002 / Evaluation of factors promoting the astaxanthin production by a unicellular green alga, Haematococcus pluvialis, with fractional factorial design / Biotechn
Choi Y-E / 2008 / Functional characterization of Fusarium verticillioides CPP1, a gene encoding putative protein phosphatase 2A catalytic subunit / Microbiology 154 : 326 ~ 3
Choi Y-E / 2010 / The cAMP signaling pathway in Fusarium verticillioides is important for conidiation, plant infection, and stress responses but not fumonisin production / Mo
Blaby IK / 2013 / Systems-level analysis of nitrogen starvation-induced modifications of carbon metabolism in a Chlamydomonas reinhardtii starchless mutant / Plant Cell 25 :
Choi Y-E / 2002 / Evaluation of factors promoting the astaxanthin production by a unicellular green alga, Haematococcus pluvialis, with fractional factorial design / Biotechn
Choi Y-E / 2008 / Functional characterization of Fusarium verticillioides CPP1, a gene encoding putative protein phosphatase 2A catalytic subunit / Microbiology 154 : 326 ~ 3
Choi Y-E / 2010 / The cAMP signaling pathway in Fusarium verticillioides is important for conidiation, plant infection, and stress responses but not fumonisin production / Mo
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