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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국미생물생명공학회 Journal of Microbiology and Biotechnology Journal of Microbiology and Biotechnology 제27권 제1호
- 발행연도
- 2017.1
- 수록면
- 57 - 66 (10page)
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Aflatoxins are classified as Group 1 (carcinogenic to humans) by the International Agency for Research on Cancer. In this study, a total of 134 fungal strains were isolated from 65 meju samples, and two fungal isolates were selected as potential aflatoxin B1 (AFB1)- biodetoxification fungi. These fungi were identified as Aspergillus oryzae MAO103 and A. oryzae MAO104 by sequencing the beta-tubulin gene. The two A. oryzae strains were able to degrade more than 90% of AFB1 (initial concentration: 40 μg/l) in a culture broth in 14 days. The mutagenic effects of AFB1 treated with A. oryzae MAO103 and MAO104 significantly decreased to 5.7% and 6.4%, respectively, in the frame-shift mutation of Ames tests using Salmonella typhimurium TA98. The base-substituting mutagenicity of AFB1 was also decreased by the two fungi. Moreover, AFB1 production by Aspergillus flavus was significantly decreased by the two A. oryzae strains on soybean-based agar plates. Our data suggest that the two AFB1- detoxifying A. oryzae strains have potential application to control AFB1 in foods and feeds.
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참고문헌 (27)
참고문헌 신청
Aibara K / 1977 / Mycotoxins in Human and Animal Health / Pathotox Publishers Inc : 151 ~ 161
Coomes TJ / 1966 / Experimental detoxification of groundnut meals containing aflatoxin / Nature 209 : 406 ~ 407
Corrier D. / 1991 / Mycotoxicosis: mechanisms of immuno-suppression / Vet. Immunol. Immunopathol 30 : 73 ~ 87
Diaz DE / 2004 / Aflatoxin binders II: reduction of aflatoxin M1 in milk by sequestering agents of cows consuming aflatoxin in feed / Mycopathologia 157 : 233 ~ 241
Doyle M / 1978 / Bisulfite degrades aflatoxin: effect of temperature and concentration of bisulfite / J. Food Prot 41 : 774 ~ 780
Coomes TJ / 1966 / Experimental detoxification of groundnut meals containing aflatoxin / Nature 209 : 406 ~ 407
Corrier D. / 1991 / Mycotoxicosis: mechanisms of immuno-suppression / Vet. Immunol. Immunopathol 30 : 73 ~ 87
Diaz DE / 2004 / Aflatoxin binders II: reduction of aflatoxin M1 in milk by sequestering agents of cows consuming aflatoxin in feed / Mycopathologia 157 : 233 ~ 241
Doyle M / 1978 / Bisulfite degrades aflatoxin: effect of temperature and concentration of bisulfite / J. Food Prot 41 : 774 ~ 780
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