지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 221 - 230 (10page)
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초록· 키워드
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Objectives: This study sought to evaluate the efficacy of collagen graft materials, as compared to other graft materials, for use in healing calvarial defects in rabbits.
Materials and Methods: Ten mm diameter calvarial defects were made in ten rabbits. The rabbits were then divided into 4 groups: control, autogenous bone graft, SureOss graft, and Teruplug graft. Bone regeneration was evaluated using histological and radiographic methods.
Results: Based on visual examination, no distinct healing profile was observed. At 4 weeks after treatment, histological analysis showed there was no bone regeneration in the control group; however, at 8 weeks after treatment, new bone formation was observed around the margin of the defective sites. In the autogenous bone graft group, new bone formation was observed at 4 weeks after treatment and mature bone was detected around the grafted bone after 8 weeks. In the SureOss graft group, at 4 weeks after treatment, acute inflammatory and multinuclear cells were noted around the grafted materials; at 8 weeks after treatment, a decrease in graft materials coupled with new bone formation were observed at the defective sites. In the Teruplug graft group, new bone formation was detected surrounding the bone margin and without signs of inflammation. There were statistically significant differences observed between the graft and control group in terms of bone density as evidenced by radiographic analysis using computed tomography (P<0.05), particularly for the autogenous bone graft group (P<0.001).
Conclusion: These results suggested that autogenous bone, SureOss and Teruplug have the ability to induce bone regeneration as compared to an untreated control group. The osteogenic potential of Teruplug was observed to be lower than that of autogenous bone, but similar to that of SureOss.
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참고문헌 (25)
참고문헌 신청
Acil Y / 2002 / Effects of bone morphogenetic protein-7 stimulation on osteoblasts cultured on different biomaterials / J Cell Biochem 86 : 90 ~ 98
Bowers GM / 1989 / Histologic evaluation of new attachment apparatus formation in humans. Part III / J Periodontol 60 : 683 ~ 693
Frame JW / 1987 / Hydroxyapatite as a biomaterial for alveolar ridge augmentation / Int J Oral Maxillofac Surg 16 : 642 ~ 655
Hislop WS / 1993 / A preliminary study into the uses of anorganic bone in oral and maxillofacial surgery / Br J Oral Maxillofac Surg 31 : 149 ~ 153
Irinakis T / 2007 / Preserving the socket dimensions with bone grafting in single sites; an esthetic surgical approach when planning delayed implant placement / J Oral Impla
Bowers GM / 1989 / Histologic evaluation of new attachment apparatus formation in humans. Part III / J Periodontol 60 : 683 ~ 693
Frame JW / 1987 / Hydroxyapatite as a biomaterial for alveolar ridge augmentation / Int J Oral Maxillofac Surg 16 : 642 ~ 655
Hislop WS / 1993 / A preliminary study into the uses of anorganic bone in oral and maxillofacial surgery / Br J Oral Maxillofac Surg 31 : 149 ~ 153
Irinakis T / 2007 / Preserving the socket dimensions with bone grafting in single sites; an esthetic surgical approach when planning delayed implant placement / J Oral Impla
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