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학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
대한구강악안면외과학회 대한구강악안면외과학회지 대한구강악안면외과학회지 제39권 제5호
발행연도
2013.1
수록면
207 - 216 (10page)

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Objectives: The purpose of this study is to analyze clinical impact factors on the survival rate, and to acquire basic clinical data for the diagnosis of oral cancer, for a determination of the treatment plan with long-term survival in oral cancer patients. Materials and Methods: Through a retrospective review of the medical records, the factors for long-term survival rate were analyzed. Thirty-seven patients, among patient database with oral cancer treated in the Department of Oral and Maxillofacial Surgery at Pusan National University Hospital within a period from March 1998 to March 2008, were selected within the study criteria and were followed-up for more than 5 years. The analyzed factors were gender, age, drinking, smoking, primary tumor site, type of cancer, TNM stage, recurrence of affected region, and metastasis of cervical lymph node. The 5-year survival rate on the impact factors was calculated statistically using the Kaplan-Meier method. Results: By classification of clinical TNM at the 1st visit, there were 11 (29.7%) cases for stage I, 11 (29.7%) cases for stage II, 3 (8.1%) cases for stage III, and 12 (32.5%) cases for stage IV. The 5-year survival rate of total oral cancer patients after the operation were 75.7%, pathological TNM stage related 5-year survival rate were as follows: stage I 90.0%, stage II 81.8%, stage III 100% and stage IV 45.5%; in which the survival rate difference by each stage was significantly observed. The recurrence of cervical lymph node was the significant impact factor for the survival rate, because only 30.0% the survival rate in recurrent cases existed. During the follow-up, there were 15 (40.5%) patients with confirmed recurrence, and the 5-year survival rate of these patients was decreased as 46.7%. Conclusion: The classification of clinical and pathological TNM stage, local recurrence after surgery, and metastasis of cervical lymph node after surgery were analyzed as the 3 most significant factors.
#Oral cancer #Survival rate #Neoplasm metastasis #Recurrence #TNM classification

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참고문헌 (27)

참고문헌 신청
Blot WJ / 1988 / Smoking and drinking in relation to oral and pharyngeal cancer / Cancer Res 48 : 3282 ~ 3287 google schola Chen JK / 1990 / Intraoral squamous cell carcinoma. Epidemiologic patterns in Connecticut from 1935 to 1985 / Cancer 66 : 1288 ~ 1296 google schola Cho JH / 1998 / Clinical and statistical analysis of the oral cancer patients: a statistical analysis of 256 cases / J Korean Assoc Maxillofac Plast Reconstr Surg 20 : 33 ~ google schola Ferlito A / 1999 / Micrometastases: have they an impact on prognosis? / Ann Otol Rhinol Laryngol 108 : 1185 ~ 1189 google schola Frierson HF Jr / 1986 / Prognostic factors in squamous cell carcinoma of the lower lip / Hum Pathol 17 : 346 ~ 354 google schola

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