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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 192 - 201 (10page)
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초록· 키워드
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Uterine fibroids (leiomyomas or myomas), benign monoclonal tumors, are the most common benign tumors inwomen. Heavy or prolonged menstrual bleeding, abnormal uterine bleeding, resultant anemia, pelvic pain, infertility,and/or recurrent pregnancy loss are generally associated with uterine fibroids. Although curative treatment of thistumor relies on surgical therapies, medical treatments are considered the first-line treatment to preserve fertilityand avoid or delay surgery. The aim of this review is to provide available and emerging medical treatment optionsfor symptomatic uterine fibroids. Literature review and consensus of expert opinion. Many uterine fibroids areasymptomatic and require no intervention, although it is advisable to follow-up patients to document stability insize and growth. Fibroid-associated symptoms include heavy menstrual bleeding and pain or pelvic discomfort. Theassociation between infertility and fibroids increases with age. Treatment options for symptomatic uterine fibroids— include medical, surgical, and radiologically guided interventions. Various medical therapies are now availablefor women with uterine fibroids, although each therapy has its own advantages and disadvantages. Currently,gonadotrophin-releasing hormone (GnRH) agonists and selective progesterone receptor modulators (SPRMs) arethe most effective medical therapies, with the most evidence to support their reduction of fibroid volume andsymptomatic improvement in menstrual bleeding. The choice of treatment depends on the patient's personaltreatment goals, as well as efficacy and need for repeated interventions.
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참고문헌 (85)
참고문헌 신청
Baird DD / 2003 / High cumulative incidence of uterine leiomyoma in black and white women: ultrasound evidence / Am J Obstet Gynecol 188:100~107
Walker CL / 2005 / Uterine fibroids: the elephant in the room / Science 308:1589~1592
Myers SL / 2012 / Self-report versus ultrasound measurement of uterine fibroid status / J Womens Health (Larchmt) 21:285~293
Ryan GL / 2005 / Role, epidemiology, and natural history of benign uterine mass lesions / Clin Obstet Gynecol 48:312~324
Zimmermann A / 2012 / Prevalence, symptoms and management of uterine fibroids: an international internet-based survey of 21,746 women / BMC Womens Health 12:6
Walker CL / 2005 / Uterine fibroids: the elephant in the room / Science 308:1589~1592
Myers SL / 2012 / Self-report versus ultrasound measurement of uterine fibroid status / J Womens Health (Larchmt) 21:285~293
Ryan GL / 2005 / Role, epidemiology, and natural history of benign uterine mass lesions / Clin Obstet Gynecol 48:312~324
Zimmermann A / 2012 / Prevalence, symptoms and management of uterine fibroids: an international internet-based survey of 21,746 women / BMC Womens Health 12:6
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