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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2016.1
- 수록면
- 415 - 420 (6page)
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초록· 키워드
오류제보하기
Primary malignant melanoma (MM) accounts for 1% of all cancers, and only 3% to 7% of these tumors occur in the female genital tract. Data are limited with respect to the basis for treatment recommendations because of the rarity of MM. The overall prognosis of melanomas of the female genital tract is very poor. Two cases of MM of the female genital tract are presented. The first case is of a 70-year-old female patient who complained of left thigh pain and underwent magnetic resonance imaging that showed cervical cancer with involvement of the vagina, bladder, and parametrium, in addition to multiple bony metastases of the proximal femur, acetabulum, and both iliac bones. The second case is of a 35-year-old female patient who suffered from vaginal bleeding for 5 months, and she was diagnosed as having primary vaginal melanoma. The patient underwent radical surgery and two additional surgeries because of recurrence of cancer in both inguinal areas. After surgery, the patient received adjuvant immunotherapy, radiation therapy, and chemotherapy. In both the aforementioned cases, the pathologic diagnosis was made after immunohistochemical analysis, i.e., the tumor cells were stained with HMB-45 and S100, and were found to be positive for both immunostains.
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참고문헌 (15)
참고문헌 신청
Xia L / 2014 / Primary malignant melanoma of the vagina : a retrospective clinicopathologic study of 44 cases / Int J Gynecol Cancer 24:149~155
Pusceddu S / 2008 / Primary uterine cervix melanoma resembling malignant peripheral nerve sheath tumor : a case report / Int J Gynecol Pathol 27:596~600
Seifried S / 2015 / Melanoma of the vulva and vagina : principles of staging and their relevance to management based on a clinicopathologic analysis of 85 cases / Ann Surg Oncol 22:1959~1966
Chang AE / 1998 / The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society / Cancer 83:1664~1678
Cantuaria G / 1998 / Primary malignant melanoma of the uterine cervix : case report and review of the literature / Prim Care Update Ob Gyns 5:159~160
Pusceddu S / 2008 / Primary uterine cervix melanoma resembling malignant peripheral nerve sheath tumor : a case report / Int J Gynecol Pathol 27:596~600
Seifried S / 2015 / Melanoma of the vulva and vagina : principles of staging and their relevance to management based on a clinicopathologic analysis of 85 cases / Ann Surg Oncol 22:1959~1966
Chang AE / 1998 / The National Cancer Data Base report on cutaneous and noncutaneous melanoma: a summary of 84,836 cases from the past decade. The American College of Surgeons Commission on Cancer and the American Cancer Society / Cancer 83:1664~1678
Cantuaria G / 1998 / Primary malignant melanoma of the uterine cervix : case report and review of the literature / Prim Care Update Ob Gyns 5:159~160
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