지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2012.1
- 수록면
- 26 - 33 (8page)
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초록· 키워드
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Background: The choice of topical agents is very important for patients with atopic dermatitis (AD) because mild to moderate AD-related symptoms and skin lesions could be significantly relieved with appropriate topical treatment. This study was performed to evaluate the effectineness of a mixed herbal extract lotion containing the extract of Sophorae Radix, Cinnamomi Cortex, Saururi Herba Seu Rhizoma and Aurantii Immaturus Fructus in relieving symptoms and skin lesions associated with AD.
Methods: A total of 24 patients who were suffering mild to moderate AD applied topical lotions, i.e. the test lotion on the right antecubital fossa and the control lotion on the left antecubital fossa twice daily for up to 4 weeks. The treatment efficacy was evaluated by the measurement of skin hydration and trans-epidermal water loss (TEWL) on the same site at each visit. Additional evaluation methods were the investigator global assessment (IGA) and the visual analogue scale visual analogue scale for pruritus.
Results: The test lotion-applied right antecubital fossa achieved more clinical improvement than the control lotion-applied left antecubital fossa. TEWL on the test side more significantly decreased than that on the control side after 4 weeks of lotion application. There were slightly more improvements in both the IGA and patient assessment of pruritus on the test side.
Conclusion: Mixed herbal extract lotions containing the extracts of Sophorae Radix, Cinnamomi Cortex, Saururi Herba Seu Rhizoma and Aurantii Immaturus Fructus can relieve symptoms, such as pruritus, in AD patients.
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등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Barel AO / 1997 / In vitro calibration of the capacitance method (Corneometer CM 825) and conductance method (Skicon-200) for the evaluation of the hydration state of the sk
Blichmann CW / 1988 / Assessment of skin moisture. Measurement of electrical conductance, capacitance and transepidermal water loss / Acta Derm Venereol 68 : 284 ~ 290
Charman CR / 2000 / Topical corticosteroid phobia in patients with atopic eczema / Br J Dermatol 142 : 931 ~ 936
Donald YM / 2008 / Atopic dermatitis, In Fitzpatrick’s dermatology in general medicine. 7th ed / McGraw-Hill : 146 ~ 158
Firooz A / 2007 / Comparison of hydration, sebum and pH values in clinically normal skin of patients with atopic dermatitis and healthy controls / Clin Exp Dermatol 32 : 321
Blichmann CW / 1988 / Assessment of skin moisture. Measurement of electrical conductance, capacitance and transepidermal water loss / Acta Derm Venereol 68 : 284 ~ 290
Charman CR / 2000 / Topical corticosteroid phobia in patients with atopic eczema / Br J Dermatol 142 : 931 ~ 936
Donald YM / 2008 / Atopic dermatitis, In Fitzpatrick’s dermatology in general medicine. 7th ed / McGraw-Hill : 146 ~ 158
Firooz A / 2007 / Comparison of hydration, sebum and pH values in clinically normal skin of patients with atopic dermatitis and healthy controls / Clin Exp Dermatol 32 : 321
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