지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2013.1
- 수록면
- 3 - 13 (11page)
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초록· 키워드
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Chronic noncancer pain is a significant and growing public health challenge in the United States. Lacking effective alternative interventions for effective chronic noncancer pain management, many physicians have turned to opioid pharmacotherapy. Increased opioid prescribing brings not only gains in therapeutic benefit but also a higher incidence of adverse drug events including increased medication misuse and opioid related mortality. Currently the United States must confront the dual problems of widespread undertreated chronic noncancer pain and a prescription opioid abuse crisis. Withholding pain relieving drugs from patients in need is unjustifiable, yet drug diversion, abuse and adverse drug events have become major social as well as medical problems. At the heart of this crisis is the lack of definitive evidence about the risk to benefit ratio of opioid pharmacotherapy for chronic noncancer pain both on an individual case and on a population basis. This article describes the extent and severity of the American chronic noncancer pain problem and the history of opioid pharmacotherapy for chronic noncancer pain in the United States. It then discusses the concept of evidence based practice and reviews current evidence supporting opioid pharmacotherapy for chronic noncancer pain as well as adverse drug events related to opioid pharmacotherapy including misuse and abuse. Finally, it considers the conflict of providing pain relief versus protecting society and reviews steps that governmental agencies, industry and others are taking to contain and ultimately resolve the problems of excessive prescribing and conflicting priorities.
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참고문헌 (27)
참고문헌 신청
/ 1997 / The use of opioids for the treatment of chronic pain. A consensus statement from the American Academy of Pain Medicine and the American Pain Society / Clin J Pain 1
Andrews CM / 2009 / Methadone-induced mortality in the treatment of chronic pain: role of QT prolongation / Cardiol J 16 : 210 ~ 217
Ballantyne JC / 2003 / Opioid therapy for chronic pain / N Engl J Med 349 : 1943 ~ 1953
Birnbaum HG / 2011 / Societal costs of prescription opioid abuse, dependence, and misuse in the United States / Pain Med 12 : 657 ~ 667
Brack A / 2011 / Immunosuppressive effects of opioids--clinical relevance / J Neuroimmune Pharmacol 6 : 490 ~ 502
Andrews CM / 2009 / Methadone-induced mortality in the treatment of chronic pain: role of QT prolongation / Cardiol J 16 : 210 ~ 217
Ballantyne JC / 2003 / Opioid therapy for chronic pain / N Engl J Med 349 : 1943 ~ 1953
Birnbaum HG / 2011 / Societal costs of prescription opioid abuse, dependence, and misuse in the United States / Pain Med 12 : 657 ~ 667
Brack A / 2011 / Immunosuppressive effects of opioids--clinical relevance / J Neuroimmune Pharmacol 6 : 490 ~ 502
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