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자료유형
학술저널
저자정보
저널정보
대한피부과학회 Annals of Dermatology Annals of Dermatology 제26권 제6호
발행연도
2014.1
수록면
722 - 726 (5page)

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Background: Alopecia areata (AA) is a common dermatologiccondition with a broad spectrum of clinical featuresand age of onset, classically characterized by nonscarringpatches of hair loss. In the past, early-onset (before adolescence)AA has been associated with various autoimmunediseases, especially atopic diseases and lupus erythematosusand demonstrates a worse prognosis compared withlate onset AA. Objective: To evaluate the differences in thecomorbidity profile of AA with regard to age at onset. Methods: We completed a retrospective study of 871 KoreanAA patients seen at our department within the last 10 years. After these patients were subdivided according to onsetbefore or after age 13 years, the two groups were comparedon the basis of their comorbid disorders, family history of AA,and hematologic test results. Results: Our results demonstratethat significantly more patients in the early-onsetgroup had a personal history of atopic dermatitis or familyhistory of AA. These findings are consistent with previousreports associating early-onset AA with autoimmune diseasesand a family history of AA in different ethnic populations. Most of the serologic test values showed no significantdifferences between the groups and the results wereconsiderably affected by age. Conclusion: This study issignificant because it is a large group study in Korean AApatients, and Korean AA patients with an onset age beforeadolescence show similar clinical manifestations to otherethnic populations.

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