지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 13 - 19 (7page)
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초록· 키워드
오류제보하기
Background: Bullous pemphigoid (BP) is a common autoimmune- mediated blistering skin disease that is significantly associated with mortality and morbidity. However, few studies regarding the mortality and comorbidity profiles of BP have been reported in Korea. Objective: To evaluate and compare the mortality, comorbidity profiles, and risk factors between patients with BP who visited our clinic and an age-matched general population of Korea. Methods: We retrospectively evaluated 103 patients diagnosed with BP between 2006 and 2013 at Chonnam National University Hospital in Gwangju, Korea. Results: The 1-year, 2-year, and 5-year mortality rates of the patients were 18.44%, 28.16%, and 42.00%, respectively. The median age was 76 years (range, 41∼96 years). The standardized mortality ratio of patients with BP was 1.83 times that of the age- and sex-matched general population of Korea. Old age at the time of diagnosis, cardiac disease and renal disease were associated with increased 5-year mortality. In addition, the prevalence of diabetes, stroke, dementia, and Parkinson’s disease was higher among BP patients than in the general population. Conclusion: The mortality rate of patients with BP is higher than that of the general Korean population. Korean patients with BP are more likely to have dementia, Parkinson’s disease, diabetes, and stroke. Risk factors for increased 5-year mortality include old age at the time of diagnosis and medical comorbidities, especially cardiac disease and renal disease.
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등록된 정보가 없습니다.
참고문헌 (41)
참고문헌 신청
Schmidt E / 2013 / Pemphigoid diseases / Lancet 381:320~332
Di Zenzo G / 2007 / Bullous pemphigoid: physiopathology, clinical features and management / Adv Dermatol 23:257~288
Ahmed AR / 1977 / Bullous pemphigoid. Clinical and immunologic follow-up after successful therapy / Arch Dermatol 113:1043~1046
Bernard P / 1995 / Survival prognosis in pemphigoid. A cohort analysis of 78 patients / Ann Dermatol Venereol 122:751~757
Bernard P / 1995 / Incidence and distribution of subepidermal autoimmune bullous skin diseases in three French regions. Bullous Diseases French Study Group / Arch Dermatol 131:48~52
Di Zenzo G / 2007 / Bullous pemphigoid: physiopathology, clinical features and management / Adv Dermatol 23:257~288
Ahmed AR / 1977 / Bullous pemphigoid. Clinical and immunologic follow-up after successful therapy / Arch Dermatol 113:1043~1046
Bernard P / 1995 / Survival prognosis in pemphigoid. A cohort analysis of 78 patients / Ann Dermatol Venereol 122:751~757
Bernard P / 1995 / Incidence and distribution of subepidermal autoimmune bullous skin diseases in three French regions. Bullous Diseases French Study Group / Arch Dermatol 131:48~52
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