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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2018.1
- 수록면
- 356 - 360 (5page)
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초록· 키워드
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Primary or metastatic malignant melanoma can mimic benign blue nevus in rare cases, making the diagnosis challenging. Herein, we report an exceptionally rare case of blue nevus-like melanoma and its blue nevus-like metastasis which was detected by catheterized urine cytology. The patient presented with blue-colored papuloplaques on his temple which were diagnosed as blue nevus-like melanoma on punch biopsies. While he was admitted for administration of chemotherapy, hematuria was detected. Catheterized urine cytology revealed singly scattered oval to spindle-shaped pigmented cells with a moderate degree of variation in shape and size. Many of them had small nuclei with indiscernible to inconspicuous nucleoli while only a few cells showed nuclear enlargement and nuclear hyperchromasia, which could be diagnostic pitfalls. Most of the cells on the smear were positive for HMB45 immunostaining, which confirmed the diagnosis of metastatic blue nevus-like melanoma. To the best of our knowledge, the present case is the first report describing cytomorphologic findings of blue nevus-like metastasis of melanoma in the urine specimen.
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참고문헌 (11)
참고문헌 신청
Busam KJ / 1999 / Metastatic melanoma to the skin simulating blue nevus / Am J Surg Pathol 23:276~282
Campa M / 2016 / Blue nevus-like metastasis of a cutaneous melanoma identified by fluorescence in situ hybridization / Am J Dermatopathol 38:695~697
Granter SR / 2001 / Melanoma associated with blue nevus and melanoma mimicking cellular blue nevus: a clinicopathologic study of 10 cases on the spectrum of so-called 'malignant blue nevus' / Am J Surg Pathol 25:316~323
Martin RC / 2009 / So-called "malignant blue nevus": a clinicopathologic study of 23 patients / Cancer 115:2949~2955
Costa S / 2016 / Melanomas associated with blue nevi or mimicking cellular blue nevi: clinical, pathologic, and molecular study of 11 cases displaying a high frequency of gna11 mutations, bap1 expression loss, and a predilection for the scalp / Am J Surg Pathol 40:368~377
Campa M / 2016 / Blue nevus-like metastasis of a cutaneous melanoma identified by fluorescence in situ hybridization / Am J Dermatopathol 38:695~697
Granter SR / 2001 / Melanoma associated with blue nevus and melanoma mimicking cellular blue nevus: a clinicopathologic study of 10 cases on the spectrum of so-called 'malignant blue nevus' / Am J Surg Pathol 25:316~323
Martin RC / 2009 / So-called "malignant blue nevus": a clinicopathologic study of 23 patients / Cancer 115:2949~2955
Costa S / 2016 / Melanomas associated with blue nevi or mimicking cellular blue nevi: clinical, pathologic, and molecular study of 11 cases displaying a high frequency of gna11 mutations, bap1 expression loss, and a predilection for the scalp / Am J Surg Pathol 40:368~377
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