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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 219 - 222 (4page)
이용수
초록· 키워드
오류제보하기
Paraneoplastic pemphigus is a rare, life-threatening autoimmune mucocutaneous blistering disease associated with underlying neoplasia, commonly lymphoproliferative tumors.
Herein we report a case of paraneoplastic pemphigus with a unique autoantibody profile associated with a malignant thymoma. A 56-year-old female patient presented with relapsing oral ulcerations accompanied by erythematous papules and patches on her extremities for 2 months. Skin and mucosal biopsies identified interface dermatitis with lichenoid lymphocytic infiltration in the upper dermis. Immunoblotting and enzyme-linked immunosorbent assays revealed that the patient had multiple autoantibodies against desmoglein 1, desmocollin 1, 2, 3, laminin gamma-1, envoplakin, and periplakin. The skin lesions completely healed following thymectomy and systemic corticosteroid therapy, but the oral ulcerations persisted through a follow-up period of over 2 years.
목차
등록된 정보가 없습니다.
참고문헌 (10)
참고문헌 신청
Anhalt GJ / 1990 / Paraneoplastic pemphigus. An autoimmune mucocutaneous disease associated with neoplasia / N Engl J Med 323 : 1729 ~ 1735
Choi Y / 2012 / Retrospective analysis of 12 Korean patients with paraneoplastic pemphigus / J Dermatol 39 : 973 ~ 981
Hong WJ / 2015 / Paraneoplastic pemphigus associated with metastatic lymphoepithelioma-like carcinoma originating from the thyroid gl / Br J Dermatol 172 : 172 ~ 831
Kelly S / 2015 / Paraneoplastic pemphigus: two cases of intra-abdominal malignancy presenting solely as treatment refractory oral ulceration / J Dermatol 42 : 300 ~ 304
Lee SE / 2010 / Paraneoplastic pemphigus / Dermatol Sin 28 : 1 ~ 14
Choi Y / 2012 / Retrospective analysis of 12 Korean patients with paraneoplastic pemphigus / J Dermatol 39 : 973 ~ 981
Hong WJ / 2015 / Paraneoplastic pemphigus associated with metastatic lymphoepithelioma-like carcinoma originating from the thyroid gl / Br J Dermatol 172 : 172 ~ 831
Kelly S / 2015 / Paraneoplastic pemphigus: two cases of intra-abdominal malignancy presenting solely as treatment refractory oral ulceration / J Dermatol 42 : 300 ~ 304
Lee SE / 2010 / Paraneoplastic pemphigus / Dermatol Sin 28 : 1 ~ 14
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