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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2017.1
- 수록면
- 39 - 47 (9page)
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Background: Treatment of congenital melanocytic nevi (CMN) with intense pulsed light (IPL) has recently produced promising results. Objective: To evaluate the clinical and histological outcomes of small-to-medium sized CMN treated with IPL alone and in combination with erbium: yttrium-aluminum- garnet (Er: YAG) laser. Methods: We performed a retrospective chart review of 26 small-to-medium sized CMN treated as described above. The reduction in visible pigmentation, signs of recurrence and any adverse skin changes were evaluated by two independent clinicians. Results: Seventeen patients completed treatment and were followedup.
Nine were not able to complete treatment due to work, change in residence, and treatment related stress. Ten patients received IPL alone (mean: 10.5 sessions) and 7 underwent treatment with IPL (mean: 7.7 sessions) and Er: YAG/IPL combination therapy (mean: 4.7 sessions). The initial treatment outcome was cleared in 5 patients and excellent in 12.
Fourteen patients (82.4%) showed CMN recurrence one year after treatment completion. The histological results from a patient with an excellent clinical outcome showed remnant nevus cells nests in the deep dermis. Conclusion: IPL treatment alone and in combination with Er: YAG laser are not definitive treatments for CMN and should not be considered as first-line treatment.
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참고문헌 (24)
참고문헌 신청
Al-Hadithy N / 2012 / Outcomes of 52patients with congenital melanocytic naevi treated with UltraPulse Carbon Dioxide and Frequency Doubled Q-Switched Nd-Yag laser / J Plast
Alikhan A / 2012 / Congenital melanocytic nevi: where are we now? Part I. Clinical presentation, epidemiology, pathogenesis, histology, malignant transformation, and neurocut
Arora H / 2015 / Lasers for nevi: a review / Lasers Med Sci 30 : 1991 ~ 2001
Berg P / 2003 / Congenital melanocytic naevi and cutaneous melanoma / Melanoma Res 13 : 441 ~ 445
Bjerring P / 2000 / Intense pulsed light source for treatment of small melanocytic nevi and solar lent
Alikhan A / 2012 / Congenital melanocytic nevi: where are we now? Part I. Clinical presentation, epidemiology, pathogenesis, histology, malignant transformation, and neurocut
Arora H / 2015 / Lasers for nevi: a review / Lasers Med Sci 30 : 1991 ~ 2001
Berg P / 2003 / Congenital melanocytic naevi and cutaneous melanoma / Melanoma Res 13 : 441 ~ 445
Bjerring P / 2000 / Intense pulsed light source for treatment of small melanocytic nevi and solar lent
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