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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2008.1
- 수록면
- 539 - 550 (12page)
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초록· 키워드
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Lung cancer is the most prevalent global cancer, ~90% of which is caused by cigarette smoking. The LNT hypothesis
has been inappropriately applied to estimate lung cancer risk due to ionizing radiation. A threshold of ~1 Gy for lung cancer
has been observed in never smokers. Lung cancer risk among nuclear workers, radiologists and diagnostically exposed
patients was typically reduced by ~40% following exposure to <100 mSv low LET radiation. The consistency and magnitude
of reduced lung cancer in nuclear workers and occurrence of reduced lung cancer in exposed non-worker populations could
not be explained by the HWE. Ecologic studies of indoor radon showed highly significant reductions in lung cancer risk. A
similar reduction in lung cancer was seen in a recent well designed case-control study of indoor radon, indicating that
exposure to radon at the EPA action level is associated with a decrease of ~60% in lung cancer. A cumulative whole-body
dose of ~1 Gy gamma rays is associated with a marked decrease in smoking-induced lung cancer in plutonium workers. Low
dose, low LET radiation appears to increase apoptosis mediated removal of -particle and cigarette smoke transformed
pulmonary cells before they can develop into lung cancer.
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등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Aurengo A / 2005 / Dose-Effect Relationships and Estimation of the Carcinogenic Effects of Low Doses of Ionizing Radiation / Executive Summary. French Academy of Sciences, French Nationa
Blot WJ / 1992 / Alcohol and cancer / Cancer Res 52 : 2119 ~ 2123
Charles L. Sanders / 2006 / Hormesis as a Confounding Factor in Epidemiological Studies of Radiation Carcinogenesis / 방사선방어학회지 31 (2) : 69 ~ 89
Chyou PH / 1992 / AM Nomura and GN Stemmermann. A prospective study of the attributable risk of cancer due to cigarette smoking / Amer. J. Public Health 82 : 37 ~ 40
Deetjen P / 1999 / Radon und Gesundheit / P. Land, Frankfurt
Blot WJ / 1992 / Alcohol and cancer / Cancer Res 52 : 2119 ~ 2123
Charles L. Sanders / 2006 / Hormesis as a Confounding Factor in Epidemiological Studies of Radiation Carcinogenesis / 방사선방어학회지 31 (2) : 69 ~ 89
Chyou PH / 1992 / AM Nomura and GN Stemmermann. A prospective study of the attributable risk of cancer due to cigarette smoking / Amer. J. Public Health 82 : 37 ~ 40
Deetjen P / 1999 / Radon und Gesundheit / P. Land, Frankfurt
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