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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 한국잠사학회 International Journal of Industrial Entomology International Journal of Industrial Entomology 제21권 제2호
- 발행연도
- 2010.1
- 수록면
- 151 - 155 (5page)
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초록· 키워드
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Protein disulfide isomerase (PDI) catalyzes the oxidation of disulfides and the isomerizatiob of incorrect disulfides in new polypeptides during folding in the oxidizing environment of the endoplasmic reticulum (ER). To increase recombinant protein hSCF (human stem cell factor) production, we have developed expression system using the Bombyx mori PDI (bPDI)as a fusion partner. bPDI gene fusion was found to improve the production of recombinant hSCFs. Thus,we conclude that bPDI gene fusion will be very useful for the large-scale production of biologically active recombinant proteins.
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참고문헌 (16)
참고문헌 신청
Fath-Goodin A / 2006 / Polydnavirus genes that enhance the baculovirus expression vector system / Adv Virus Res 68 : 75 ~ 90
Frand AR / 2000 / Pathways for protein disulphide bond formation / Trends Cell Biol 10 : 203 ~ 210
Galli SJ / 1994 / The kit ligand, stem cell factor / Adv Immunol 55 : 1 ~ 96
Goo TW / 2002 / Molecular characterization of a Bombyx mori protein disulfide isomerase (bPDI) / Cell Stress Chaperones 7 : 118 ~ 125
Goo TW / 2008 / Domain a' of Bombyx mori protein disulfide isomerase has chaperone activity / Z Naturforsch C 63 : 435 ~ 439
Frand AR / 2000 / Pathways for protein disulphide bond formation / Trends Cell Biol 10 : 203 ~ 210
Galli SJ / 1994 / The kit ligand, stem cell factor / Adv Immunol 55 : 1 ~ 96
Goo TW / 2002 / Molecular characterization of a Bombyx mori protein disulfide isomerase (bPDI) / Cell Stress Chaperones 7 : 118 ~ 125
Goo TW / 2008 / Domain a' of Bombyx mori protein disulfide isomerase has chaperone activity / Z Naturforsch C 63 : 435 ~ 439
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An Analysis of Heterosis in the Silkworm,Bombyx mori(L.)
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Microsporidian Disease of the Silkworm, Bombyx mori L. (Lepidoptera: Bombycidae)
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