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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Menopause is a critical stage of women’s life associated with various complaints and distresses. Vasomotor symptoms (VMS), such as hot flushes, night sweats, sleep disturbances, and fatigue, are the most common menopause symptoms affecting about 50% to 80% of middle-aged women. Obviously, these symptoms, resulting from estrogen deficiency during menopause, can exert negative effects on women’s health and quality of life and thus require to be managed through approaches such as hormone replacement therapy (HRT). Many herbal treatments for menopause symptoms contain and its components such as 8-prenylnaringenin, 6-PN, isoxanthohumol and xanthohumol. Recent in-vivo studies have highlighted the ability of 8-prenylnaringenin to reduce serum-luteinizing hormone (LH) and follicle-stimulating hormone (FSH), to increase serum prolactin levels and uterine weight, and to induce vaginal hyperplastic epithelium. Previous research has shown that hops extract can strongly bind to both estrogen receptors, stimulate alkaline phosphatase activity in Ishikawa cells, and upregulate presenelin-2 and progesterone receptor mRNA in Ishikawa cells. Numerous clinical trials have documented significant reductions in the frequency of hot flushes following the administration of hop-containing preparations. Nevertheless, further clinical trials with larger sample size and longer follow-up are warranted to confirm such benefits. (J Menopausal Med 2016;22:62-64)
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참고문헌 (18)
참고문헌 신청
Abdi F / 2016 / Protocol for systematic review and meta-analysis: hop (Humulus lupulus L.) for menopausal vasomotor symptoms / BMJ Open 6:e010734
Dennerstein L / 2007 / New findings from non-linear longitudinal modelling of menopausal hormone changes / Hum Reprod Update 13:551~557
Abdi F / 2016 / Effects of hormone replacement therapy on immunological factors in the postmenopausal period / Climacteric 19:234~239
Fatemeh Shobeiri / 2016 / Quality of Life in Postmenopausal Women in Iran: A Population-based Study / 대한폐경학회지 22(1):31~38
Birrer N / 2016 / Is hormone replacement therapy safe in women with a BRCA mutation?: A systematic review of the contemporary literature / Am J Clin Oncol
Dennerstein L / 2007 / New findings from non-linear longitudinal modelling of menopausal hormone changes / Hum Reprod Update 13:551~557
Abdi F / 2016 / Effects of hormone replacement therapy on immunological factors in the postmenopausal period / Climacteric 19:234~239
Fatemeh Shobeiri / 2016 / Quality of Life in Postmenopausal Women in Iran: A Population-based Study / 대한폐경학회지 22(1):31~38
Birrer N / 2016 / Is hormone replacement therapy safe in women with a BRCA mutation?: A systematic review of the contemporary literature / Am J Clin Oncol
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