개인구독
소속 기관이 없으신 경우, 개인 정기구독을 하시면 저렴하게
논문을 무제한 열람 이용할 수 있어요.
지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Objectives: The aim of the present study is to evaluate the long term effects of estrogen-progestogen therapy (EPT) on uterine myomas volume in postmenopausal women.
Methods: We performed a retrospective analysis on postmenopausal women with asymptomatic uterine myoma during the period between April, 2008 and September, 2012. Postmenopause was defined as amenorrhea for longer than a year or serum follicle stimulating hormone levels higher than 40 IU/L. The volume of the myoma was assessed by transvaginal ultrasonography for every 6 months after administration of EPT.
Results: Thirty-eight women were included in the study, with 32 in the EPT group and 6 in the control group. Overall, uterine myoma volume (mean ± standard deviation, cm3) in the EPT group was 19.5 ± 24.6 at baseline, and those at 6 and 12 months were 24.7 ± 35.1 and 28.5 ± 56.4, respectively. Myoma volume did not change significantly with EPT, and these changes were not significantly different from the control group. Myoma volume changes were not significantly different in the subgroups according to the route of estrogen administrations and the method of progestogen administrations. Clinically significant volume increases during one year of EPT was noted in 28.1% (9/32), however, only one showed transient increases.
Conclusion: Our results suggest that treating postmenopausal woman with EPT on a long-term basis does not increase the volume of uterine myomas.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Ang WC / 2001 / Effect of hormone replacement therapies and selective estrogen receptor modulators in postmenopausal women with uterine leiomyomas: a literature review / Clim
Chrapusta S / 1990 / Estrogen and progestin receptor levels in uterine leiomyomata: relation to the tumour histology and the phase of menstrual cycle / Eur J Gynaecol Oncol
Colacurci N / 2000 / Effects of hormone replacement therapy on postmenopausal uterine myoma / Maturitas 35 : 167 ~ 173
Fedele L / 2000 / A randomized study of the effects of tibolone and transdermal estrogen replacement therapy in postmenopausal women with uterine myomas / Eur J Obstet Gynec
Giuntoli RL, 2nd / 2003 / Retrospective review of 208 patients with leiomyosarcoma of the uterus: prognostic indicators, surgical management, and adjuvant therapy / Gynecol
Chrapusta S / 1990 / Estrogen and progestin receptor levels in uterine leiomyomata: relation to the tumour histology and the phase of menstrual cycle / Eur J Gynaecol Oncol
Colacurci N / 2000 / Effects of hormone replacement therapy on postmenopausal uterine myoma / Maturitas 35 : 167 ~ 173
Fedele L / 2000 / A randomized study of the effects of tibolone and transdermal estrogen replacement therapy in postmenopausal women with uterine myomas / Eur J Obstet Gynec
Giuntoli RL, 2nd / 2003 / Retrospective review of 208 patients with leiomyosarcoma of the uterus: prognostic indicators, surgical management, and adjuvant therapy / Gynecol
이 논문의 저자 정보
최근 본 자료
댓글(0)
0