지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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To evaluate the effects of transdermal estrogen therapy on bone mineral density (BMD) in postmenopausal Koreanwomen.
Methods: A total of 149 healthy postmenopausal women were retrospectively evaluated: 100 were on hormone therapy (HT) and49 were the control group. For the HT group, 54 applied estrogen transdermally using either a patch (n = 21) or gel (n = 33), and46 took estrogen orally (conjugated estrogen 0.625 mg or equivalent). Demographic profiles and changes in BMD over two yearswere compared according to the route of the estrogen.
Results: No differences were found in age, age at menopause, parity, body mass index, and type of menopause among the oral,transdermal and control groups. Compared with controls, HT significantly increased BMD after 2 years in both the lumbar spineand the total hip. The increases in BMD at both lumbar spine and hip were comparable between the oral and transdermal groups.
There were also no differences in BMD changes according to progestogen addition in either the oral or transdermal groups.
Conclusion: Transdermal estrogen therapy increases BMD, comparable to oral estrogen, in postmenopausal Korean women. (JMenopausal Med 2014;20:111-117)
목차
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참고문헌 (22)
참고문헌 신청
Anderson GL / 2004 / Effects of conjugated equine estrogen in postmenopausal women with hysterectomy: the Women’s Health Initiative randomized controlled trial / JAMA 291 :
Carroll N / 2010 / A review of transdermal nonpatch estrogen therapy for the management of menopausal symptoms / Womens Health (Larchmt) 19 : 47 ~ 55
Cauley JA / 2003 / Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women’s Health Initiative randomized trial / JAMA 290 : 1729 ~ 1738
Cetinkaya MB / 2002 / Alper T. Comparison of the effects of transdermal estrogen, oral estrogen, and oral estrogen-progestogen therapy on bone mineral density in postmenopau
Checa MA / 2005 / Timing of follow-up densitometry in hormone replacement therapy users for optimal osteoporosis prevention / Osteoporos Int 16 : 937 ~ 942
Carroll N / 2010 / A review of transdermal nonpatch estrogen therapy for the management of menopausal symptoms / Womens Health (Larchmt) 19 : 47 ~ 55
Cauley JA / 2003 / Effects of estrogen plus progestin on risk of fracture and bone mineral density: the Women’s Health Initiative randomized trial / JAMA 290 : 1729 ~ 1738
Cetinkaya MB / 2002 / Alper T. Comparison of the effects of transdermal estrogen, oral estrogen, and oral estrogen-progestogen therapy on bone mineral density in postmenopau
Checa MA / 2005 / Timing of follow-up densitometry in hormone replacement therapy users for optimal osteoporosis prevention / Osteoporos Int 16 : 937 ~ 942
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