지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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The definition of anaphylaxis is 'a serious, life-threatening generalized or systemic hypersensitivity reaction' and is considered as the life threatening adverse drug reaction. We experienced a case of cefotetan induced anaphylaxis with negative pre-skin test, used for surgical prophylaxis. A 82-year-old female was scheduled for total knee replacement therapy. She had no previous history of allergy and her skin test results were also negative. On her right knee surgery,she underwent cefotetan therapy as a surgical prophylaxis for a week with no problems identified. Next left knee surgery,she also received the prophylaxis of intravenous cefotetan. However, a few minutes later, anaphylactic reaction developed with vomiting, severe hypotension, bronchospasm, and dyspnea. After immediate intensive care treatment,she recovered without significant complications. Though commonly used laboratory data in case reports, such as the specific IgE, tryptase, histamine, or allergic skin prick test were limited, we successfully confirmed anaphylaxis based on clinical criteria for diagnosing anaphylaxis based on WAO 2011 guideline with through concurrent patient°Øs medical history review and the process of identifying the causes.
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참고문헌 (30)
참고문헌 신청
Antunez C / 2006 / Immediate allergic reactions to cephalosporins: evaluation of crossreactivity with a panel of penicillins and cephalosporins / J Allergy Clin Immunol 117
Antunez C / 2006 / Immediate reactivity with a panel of penicillins and cephalosporins / J Allergy Clin Immunol 117 : 404 ~ 410
Bloomberg RJ / 1988 / Cefotetan-induced anaphylaxis / Am J Obstet Gynecol 159 : 125 ~ 126
Demirkan K / 2006 / Anaphylactic reaction to drugs commonly used for gastrointestinal system diseases:3 case reports and review of the literature / J Investig Allergol Clin
Fisher M / 1994 / Anaphylaxis during anaesthesia: current aspects of diagnosis and prevention / Eur J Anaesthesiol 11 : 263 ~ 284
Antunez C / 2006 / Immediate reactivity with a panel of penicillins and cephalosporins / J Allergy Clin Immunol 117 : 404 ~ 410
Bloomberg RJ / 1988 / Cefotetan-induced anaphylaxis / Am J Obstet Gynecol 159 : 125 ~ 126
Demirkan K / 2006 / Anaphylactic reaction to drugs commonly used for gastrointestinal system diseases:3 case reports and review of the literature / J Investig Allergol Clin
Fisher M / 1994 / Anaphylaxis during anaesthesia: current aspects of diagnosis and prevention / Eur J Anaesthesiol 11 : 263 ~ 284
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