지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Objective: This study aims to explore the perception of off-label use of medications and the provision of informed consentsfrom the general public’s perspective. Methods: The study subjects (n=291) were recruited from 7 cities in Koreathrough a convenience sampling method. The self-administered questionnaire with 13 items was issued and collected. The study subjects who have had a pharmaceutical job were excluded. Results: The total of 231 respondents wasincluded. Only 23% of respondents were familiar with the concept of off-label use of medications. Eighty five percentof respondents (n=196) stated that the prescribers should explain the off-label use of a medication to their patients. Thepreferred method for delivering the message was the oral explanation (n=122, 53%), followed by oral explanation plusa pamphlet (n=94, 41%). The safety issue is the most concerned aspect regarding the off-label drug use, also effectivenessand insurance coverage. The majority of respondents (n=217, 94%) agreed that the prescriber should get a consentfrom patients before prescribing medications for off-label use. They preferred written consent to oral consent (140vs. 77). Conclusion: This study demonstrated general publics are infrequently aware of off-label use of medications. Itis important to raise public awareness of the off-label use of medications and to openly discuss its pros and cons forsafe and effective drug therapy.
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등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Brosgart CL. / 1996 / Off-label drug use in human immunodeficiency virus disease / J Acquir Immune Defic Syndr Hum Retrovirol 12 (1) : 56 ~ 62
Cuzzolin L. / 2006 / Off-label and unlicensed prescribing for newborns and children in different settings : a review of the literature and a consideration about drug safety
Dresser R. / 2009 / Off-label prescribing : A call for heightened professional and government oversight / J Law Med Ethics 37 (3) : 476 ~ 496
EURORDIS / 2008 / EURORDIS response to the European Commission Public Consultation "Legal proposal on information to patients"
Goldberg AB. / 2001 / Misoprostol and pregnancy / New Engl J Med 344 (1) : 38 ~ 47
Cuzzolin L. / 2006 / Off-label and unlicensed prescribing for newborns and children in different settings : a review of the literature and a consideration about drug safety
Dresser R. / 2009 / Off-label prescribing : A call for heightened professional and government oversight / J Law Med Ethics 37 (3) : 476 ~ 496
EURORDIS / 2008 / EURORDIS response to the European Commission Public Consultation "Legal proposal on information to patients"
Goldberg AB. / 2001 / Misoprostol and pregnancy / New Engl J Med 344 (1) : 38 ~ 47
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