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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Objectives: The present study assessed the prevalence of the potentially inappropriate medication (PIM) use in Korean elderly patients with Parkinson’s disease. In addition, this study examined risk factors that affect PIM use. Method: A retrospective, observational study was conducted using Korean National Health Insurance claims database of 2009. PIM use in Parkinson’s disease patients aged 65 years or older was examined based on 2012 Beers Criteria. Multivariable logistic regression was conducted to identify risk factors for PIM use. Results: Among 5,277 elderly patients with Parkinson’s disease, 88.9% of patients used PIM(s) at least once. The average number of PIM items used per patient was 4.2. PIM use ratio, the proportion of total amount of PIMs to all medications per patient, was 12.6%. Frequently used PIM therapeutic classes were benzodiazepines (32.7%), firstgeneration antihistamines (19.2%), and prokinetics (17.5%). Individual PIMs most commonly used included chlorpheniramine (11.4%), levosulpiride (10.9%), diazepam (9.0%), and alprazolam (7.6%). Women (odds ratio [OR] 1.14, 95% confidence interval [CI] 1.11-1.16), medical aid (OR 1.18, 95% CI 1.15-1.21), and long-term facilities (OR 2.43, 95% CI 2.22-2.65) were shown to be risk factors associated with PIM use. Of particular, wide variation in PIM use was associated with the types of healthcare facility. Conclusion: The PIM prevalence was very high in elderly Parkinson’s disease patients. Nationally effective and systematic efforts to identify and prevent PIM use should be made to ensure patient safety and to improve quality of care in the elderly.
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참고문헌 (28)
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Assessing Medication Use Quality in Older Outpatients Using the Beers Criteria: Findings from a Single-Center Retrospective Study
Annals of geriatric medicine and research
2023 .06
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Potentially Inappropriate Medications by Beers Criteria in Older Outpatients: Prevalence and Risk Factors
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2016 .01
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Drug Utilization Review 시행 전후 3차 의료기관에서의 노인주의약품 외래처방 현황 분석
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Validation of Pediatric Index of Mortality 3 for Predicting Mortality among Patients Admitted to a Pediatric Intensive Care Unit
Acute and Critical Care
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Potentially Inappropriate Medication Use among Nursing Home Residents: Medication Errors Associated with Pro re nata Medications and the Importance of Pill Burden
Annals of geriatric medicine and research
2022 .09
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PIM Kinase as an Executional Target in Cancer
대한암예방학회지
2018 .01
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Aberrant Expression of Pim-3 Promotes Proliferation and Migration of Ovarian Cancer Cells
Asian Pacific journal of cancer prevention : APJCP
2015 .01
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상급종합병원 근처의 한 지역약국 처방전 분석에 의한 노인 환자의 다약제복용과 약제비용 및 잠재적으로 부적절한 약물사용 관련 위험인자
한국임상약학회지
2015 .01
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지역사회 거주 노인을 위한 약물사용검토 도구에 대한 체계적 문헌고찰
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Development of a Consensus List of Potentially Inappropriate Medications for Korean Older Adults
Annals of geriatric medicine and research
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Potentially Inappropriate Medications and Regimen Complexity on Readmission of Elderly Patients with Polypharmacy: A Retrospective Study
한국임상약학회지
2023 .03
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단일 상급종합병원에서 노인 환자의 다제약물 복약상담 현황
병원약사회지
2023 .02
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Emerging Nondopaminergic Medications for Parkinson’s Disease: Focusing on A2A?Receptor Antagonists and GLP1 Receptor Agonists
Journal Of Movement Disorders
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The Four Square Step Test for Assessing Cognitively Demanding Dynamic Balance in Parkinson’s Disease Patients
Journal Of Movement Disorders
2021 .09
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만성 심부전 노인 환자에서 다약제 사용에 따른 위험성 평가
병원약사회지
2021 .01
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Polypharmacy, Potentially Inappropriate Medications, and Dysphagia in Older Inpatients: A Multi-Center Cohort Study
Annals of geriatric medicine and research
2024 .03
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파킨슨병 환자의 건강관리 경험
한국간호교육학회지
2020 .11
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Predictors of Low Medication Adherence in patients with Parkinson’s Disease
성인간호학회 학술대회
2017 .11
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파킨슨병 독거노인의 질병체험
성인간호학회지
2018 .08
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The Impact of Pharmacist Medication Reviews on Geriatric Patients: A Scoping Review
Korean Journal of Family Medicine
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