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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
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Cytochrome-c-oxidase in mitochondria membrane is one of the most important factors for energy generation in the
cell. As well as it is electron transfer enzyme, it is also heavily related to the apoptosis and other pathologic conditions.
Meanwhile, porin is a protein located in inner and outer membranes of mitochondria, which is assumed to be functionally
correlated with cytochrome-c-oxidase. It functions as forming electron transfer chain and conveying ATP. Therefore,
using the immune-microscopy, It compared the distribution of cytochrome-c-oxidase and porin to figure out the
formation and changes on cytochrome-c-oxidase in mitochondrial cristae.
The sarcroplasm of cardic muscle tissue has many mitochondria. They are classified into two groups: the mitochondria
with many cytochrome-c-oxidase and the mitochondria with only porins. The mitochondria with porins had few
cytochrome-c-oxidases in their membrane; in contrast, the other mitochondria with rich cytochrome-c-oxidase had few
porins in their walls. In addition, according to the location of the tissue in bovine heart, distribution of those kind of
mitochondria had been clearly separated. As a result, it could be assumed that immature mitochondria has many porins to
transfer the protein materials from sarcroplasm through the porins, and they made cytochrome-c-oxidase until it is
enough, and then they decreased the porin and maintained minimum number of the porin.
목차
등록된 정보가 없습니다.
참고문헌 (19)
참고문헌 신청
Abrecht H / 2000 / Purification and characterization of two voltage-dependent anion channel isoforms from plant seeds / Plant Physiol 124 : 1181 ~ 1190
Colombini M / 1979 / A candidate for the permeability pathway of the outer mitochondrial membrane / Nature 279 (5714) : 643 ~ 645
De Pinto V / 1989 / Characterization of the mitochondrial porin from Drosophila melanogaster / Biochim Biophys Acta 987 : 1 ~ 7
Hanson BJ / 2002 / An immunocytochemical approach to detection of mitochondrial disorders / The journal of histochemistry & cytochemistry 50 (10) : 1281 ~ 1288
Heins L / 1994 / Biochemical, molecular, and functional characterization of porin isoforms from potato mitochondria / J Biol Chem 269 (42) : 26402 ~ 26410
Colombini M / 1979 / A candidate for the permeability pathway of the outer mitochondrial membrane / Nature 279 (5714) : 643 ~ 645
De Pinto V / 1989 / Characterization of the mitochondrial porin from Drosophila melanogaster / Biochim Biophys Acta 987 : 1 ~ 7
Hanson BJ / 2002 / An immunocytochemical approach to detection of mitochondrial disorders / The journal of histochemistry & cytochemistry 50 (10) : 1281 ~ 1288
Heins L / 1994 / Biochemical, molecular, and functional characterization of porin isoforms from potato mitochondria / J Biol Chem 269 (42) : 26402 ~ 26410
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