지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
Endocirne disruptors (EDs) can cause fertility decrease, developmental disorder, and even cancer in animals. Until 90’s, EDs were used in various synthetic products including paints, coatings, detergents, plastics, and plasticizers. Currently, in several countries, the production, trade and use of EDs or EDs-suspected chemicals have been regulated while activity to screen the alternatives for EDs including bisphenol-A, phthalate and nonylphenol is active. Although various toxicity test method was developed and applied for screening of alternatives, however, the safety of alternatives has been not fully demonstrated. Some alternatives have high structural similarity with existing EDs, raising the possible risk of endocrine disruption by alternatives. In an effort to develop the safe alternatives, we reviewed the effects of EDs such as bisphenol-A, phthalates, nonylphenol and their substituents. In addition, in-silico analysis for endocrine disrupting activities of some alternatives was presented.
목차
등록된 정보가 없습니다.
참고문헌 (27)
참고문헌 신청
Alvarez-Chavez CR. / 2009 / Sustainability of Bio-Polymers : Comparative Analysis of Corn and Potato Based Bio-Polymers / Doctoral / University of Massachusetts
Api AM. / 2001 / Toxicological profile of diethyl phthalate : a vehicle for fragrance and cosmetic ingredients / Food Chem. Toxicol 39 : 97 ~ 108
Baba K. / 2009 / Bisphenol A disrupts Notch signaling by inhibiting gamma-secretase activity and causes eye dysplasia of Xenopus laevis / Toxicol. Sci 108 : 344 ~ 355
Bae S. / 2012 / Associations of bisphenol A exposure with heart rate variability and blood pressure / Hypertension 60 : 786 ~ 793
Bittner G. / 2012 / Comment on"Lack of androgenicity and estrogenicity of the three monomers used in Eastman’s TritanTM copolyesters"by Osimitz et al / Food Chem. Toxicol 50
Api AM. / 2001 / Toxicological profile of diethyl phthalate : a vehicle for fragrance and cosmetic ingredients / Food Chem. Toxicol 39 : 97 ~ 108
Baba K. / 2009 / Bisphenol A disrupts Notch signaling by inhibiting gamma-secretase activity and causes eye dysplasia of Xenopus laevis / Toxicol. Sci 108 : 344 ~ 355
Bae S. / 2012 / Associations of bisphenol A exposure with heart rate variability and blood pressure / Hypertension 60 : 786 ~ 793
Bittner G. / 2012 / Comment on"Lack of androgenicity and estrogenicity of the three monomers used in Eastman’s TritanTM copolyesters"by Osimitz et al / Food Chem. Toxicol 50
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