지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
A cell is the product of a long period of evolution and can be represented as an optimized
system (homeostasis). Stimuli from the outside environment are received by sensory apparatus
on the surface of the cell and transferred through complicated pathways and eventually regulate
gene expression. These signals affect cell physiology, growth, and development, and the
interaction among genes in the signal transduction pathway is a critical part of the regulation. In
this study, the interactions of deletion mutants and overexpression of the extracopies of the genes
were used to understand their relationships to each other. Also, green fluorescent protein (GFP
reporter gene) was fused to the regulatory genes to elucidate their interactions. Cooverexpression
of the two genes in extracopy plasmids suggested that patS acts at the downstream of hetR in the
regulatory network. The experiments using gfp fusion in different genetic background cells also
indicated the epistasis relationships between the two genes. A model describing the regulatory
network that controls cell development is presented.
목차
등록된 정보가 없습니다.
참고문헌 (20)
참고문헌 신청
Black TA / 1993 / Spatial expression and autoregulation of hetR, a gene involved in the control of heterocyst development in Anabaena / Mol. Microbiol 9:77~84
Borthakur PB / 2005 / Inactivation of patS and hetN causes lethal levels of heterocyst differentiation in the filamentous cyanobacterium Anabaena sp. PCC 7120 / Mol. Microbiol 57:111~123
Buikema WJ / 1991 / Characterization of a gene controlling heterocyst differentiation in the cyanobacterium Anabaena 7120 / Genes Dev 5:321~330
Buikema WJ / 2001 / Expression of the Anabaena hetR gene from a copper-regulated promoter leads to heterocyst differentiation under repressing conditions / Proc. Natl. Acad. Sci. U S A 98:2729~2734
Cai YP / 1990 / Use of a conditionally lethal gene in Anabaena sp. strain PCC 7120 to select for double recombinants and to entrap insertion sequences / J. Bacteriol 172:3138~3145
Borthakur PB / 2005 / Inactivation of patS and hetN causes lethal levels of heterocyst differentiation in the filamentous cyanobacterium Anabaena sp. PCC 7120 / Mol. Microbiol 57:111~123
Buikema WJ / 1991 / Characterization of a gene controlling heterocyst differentiation in the cyanobacterium Anabaena 7120 / Genes Dev 5:321~330
Buikema WJ / 2001 / Expression of the Anabaena hetR gene from a copper-regulated promoter leads to heterocyst differentiation under repressing conditions / Proc. Natl. Acad. Sci. U S A 98:2729~2734
Cai YP / 1990 / Use of a conditionally lethal gene in Anabaena sp. strain PCC 7120 to select for double recombinants and to entrap insertion sequences / J. Bacteriol 172:3138~3145
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