지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Background: Onychomycosis is one of the most common diseases of the nails accounting for up to 50% of all nail problems. There are many literatures on the cure rate and duration for complete cure according to the various factors. However, little information is available regarding duration required for negative conversion of KOH mount.
Objective: The purpose of this study was to evaluate the duration required for negative conversion of KOH mount in patients with toenail onychomycosis according to the clinical factors and treatment regimens.
Methods: Medical records of 325 patients with onychomycosis between May 2001 and February 2012 were reviewed retrospectively to obtain the following information: age, sex, presence of diabetes mellitus (DM), extent of nail involvement, therapeutic methods, and result of KOH mount at each timepoint.
Results: Extent of nail involvement, old age (≥60) and DM were negatively associated with the duration required for conversion of KOH mount. Extent of nail involvement also negatively affected the rate of conversion of KOH mount at week 48. Positive KOH mount at week 28 was negatively associated with complete cure.
Conclusions: Extent of nail involvement, old age, and DM can prolong the duration required for negative conversion of KOH mount. Also, positive KOH mount at week 28 had negative effect on the cure of onychomycosis.
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참고문헌 (23)
참고문헌 신청
Baran R / 2007 / A multicentre, randomized, controlled study of the efficacy, safety and cost-effectiveness of a combination therapy with amorolfine nail lacquer and oral te
Brautigam M / 1998 / Successful treatment of toenail onychomycosis with terbinafine and itraconasole gives long term benefits / Br Med J 317 : 1084 ~ 1085
Davies RR / 1968 / Mycological tests and onychomycosis / J Clin Pathol 21 : 729 ~ 730
Effendy I / 2005 / Epidemiology and clinical classification of onychomycosis / J Eur Acad Dermatol Venereol 19 (Suppl 1) : 8 ~ 12
Gentles JC / 1971 / Laboratory investigations of dermatophyte infections of nails / Sabouraudia 9 : 149 ~ 152
Brautigam M / 1998 / Successful treatment of toenail onychomycosis with terbinafine and itraconasole gives long term benefits / Br Med J 317 : 1084 ~ 1085
Davies RR / 1968 / Mycological tests and onychomycosis / J Clin Pathol 21 : 729 ~ 730
Effendy I / 2005 / Epidemiology and clinical classification of onychomycosis / J Eur Acad Dermatol Venereol 19 (Suppl 1) : 8 ~ 12
Gentles JC / 1971 / Laboratory investigations of dermatophyte infections of nails / Sabouraudia 9 : 149 ~ 152
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