Chronological changes in epidemiologic features of patients with gallstones over the last 20 years in a single large-volume Korean center

Jiyong Zhao; Hongbeom Kim; Youngmin Han; Yoo Jin Choi; Yoonhyeong Byun; Wooil Kwon; Jin-Young Jang

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자료유형: 학술저널

저자정보: Jiyong Zhao (Seoul National University College of Medicine) Hongbeom Kim (Seoul National University College of Medicine) Youngmin Han (Seoul National University College of Medicine) Yoo Jin Choi (Seoul National University College of Medicine) Yoonhyeong Byun (Seoul National University College of Medicine) Wooil Kwon (Seoul National University College of Medicine) Jin-Young Jang (Seoul National University College of Medicine)

저널정보: 대한외과학회 Annals of Surgical Treatment and Research Annals of Surgical Treatment and Research Vol.97 No.3

발행연도: 2019.9

수록면: 136 - 141 (6page)

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Purpose: South Korea has a high prevalence of gallstones, the type of which could be influenced by changes in diet and socioeconomic status. Here we aimed to investigate the epidemiological characteristics and changing patterns of gallstones over the past 20 years in Korea.
Methods: A total of 5,808 patients who underwent cholecystectomy due to gallstones at Seoul National University Hospital between 1996 and 2015 were analyzed. Patients were divided into 4 subgroups: period 1 (1996–2000, n = 792), period 2 (2001–2005, n = 1,215), period 3 (2006–2010, n = 1,525), period 4 (2011–2015, n = 2,276). Gallstones were classified by type: pure cholesterol (PC), mixed cholesterol (MC), calcium bilirubinate (CB), black pigment (BP), and combination (COM).
Results: The female to male ratio was 1.16 with mean ages of 53.6 and 55.3 years old, respectively. The ratio of cholesterol stones to pigment stones was 0.96:1. The mean age and male to female ratio of the patients increased over time. The proportion of cholesterol vs pigment stone did not differ significantly. Proportions of PC and MC stone subtypes did not change notably, whereas proportion of BP stones increased (34.0% to 45.5%), and CB stones decreased (20.7% to 5.3%).
Conclusion: Gallstone types and occurrences were affected by environmental changes, and pigment stones remained common in Korea. Although no distinct increase in cholesterol stones was noted, the proportion of CB stones decreased. As the mean age at gallstone presentation increases, BP stones could become more prevalent.

#Cholecystolithiasis #Cholelithiasis #Classification #Gallstones

참고문헌 (23)

참고문헌 신청

Lee JK / 1997 / Prevalence and risk factors of gallstone in health screening people / Korean J Gastroenterol 29:85~92

정윤진 / 2007 / 건강검진자에서 담낭 담석의 유병률과 위험인자 / 대한내과학회지 72(5):480~490

Stinton LM / 2010 / Epidemiology of gallstones / Gastroenterol Clin North Am 39:157~169

Suzuki N / 1986 / A new classification of gallstone / J Biliary Tract Pancreas 7:1467~1470

James D / 1999 / Ethnic and sex differences in selection for admission to Nottingham University Medical School / BMJ 319:351~352

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