지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 25 - 31 (7page)
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초록· 키워드
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Background/Aims: Although abdominal visceral fat has been associated with erosive esophagitis in cross-sectional studies, there are few data on the longitudinal effect. We evaluated the effects of abdominal visceral fat change on the regression of erosive esophagitis in a prospective cohort study. Methods: A total of 163 participants with erosive esophagitis at baseline were followed up at 34 months and underwent esophagogastroduodenoscopy and computed tomography at both baseline and follow-up. The longitudinal effects of abdominal visceral fat on the regression of erosive esophagitis were evaluated using relative risk (RR) and 95% confidence intervals (CIs). Results: Regression was observed in approximately 49% of participants (n=80). The 3rd (RR, 0.13; 95% CI, 0.02 to 0.71) and 4th quartiles (RR, 0.07; 95% CI, 0.01 to 0.38) of visceral fat at follow-up were associated with decreased regression of erosive esophagitis. The highest quartile of visceral fat change reduced the probability of the regression of erosive esophagitis compared to the lowest quartile (RR, 0.10; 95% CI, 0.03 to 0.28). Each trend showed a dose-dependent pattern (p for trend <0.001). The presence of baseline Helicobacter pylori increased the regression of erosive esophagitis (RR, 2.40; 95% CI, 1.05 to 5.48). Conclusions: Higher visceral fat at follow-up and a greater increase in visceral fat reduced the regression of erosive esophagitis in a dose-dependent manner.
목차
등록된 정보가 없습니다.
참고문헌 (18)
참고문헌 신청
Kim N / 2008 / The prevalence of and risk factors for erosive oesophagitis and non-erosive reflux disease : a nationwide multicentre prospective study in Korea / Aliment Pharmacol Ther 27:173~185
Cho YS / 2005 / Prevalence and clinical spectrum of gastroesophageal reflux : a population-based study in Asan-si, Korea / Am J Gastroenterol 100:747~753
Nam SY / 2009 / Obesity and weight gain as risk factors for erosive oesophagitis in men / Aliment Pharmacol Ther 29:1042~1052
Nam SY / 2010 / Abdominal visceral adipose tissue volume is associated with increased risk of erosive esophagitis in men and women / Gastroenterology 139:1902~1911
Corley DA / 2007 / Abdominal obesity, ethnicity and gastro-oesophageal reflux symptoms / Gut 56:756~762
Cho YS / 2005 / Prevalence and clinical spectrum of gastroesophageal reflux : a population-based study in Asan-si, Korea / Am J Gastroenterol 100:747~753
Nam SY / 2009 / Obesity and weight gain as risk factors for erosive oesophagitis in men / Aliment Pharmacol Ther 29:1042~1052
Nam SY / 2010 / Abdominal visceral adipose tissue volume is associated with increased risk of erosive esophagitis in men and women / Gastroenterology 139:1902~1911
Corley DA / 2007 / Abdominal obesity, ethnicity and gastro-oesophageal reflux symptoms / Gut 56:756~762
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