지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 138 - 146 (9page)
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Purpose: Congenital pulmonary airway malformation (CPAM)－a rare developmental anomaly－affects the lower respiratory tract in newborns. By comparing the reliability of diagnostic tools and identifying predictive factors for symptoms, we provide comprehensive clinical data for the proper management of CPAM. Methods: We reviewed the medical records of 66 patients with prenatally diagnosed CPAM delivered at Severance Children’s Hospital between January 2005 and July 2017. Results: We enrolled 33 boys and 33 girls. Their mean gestational age and birth weight were 38.8 weeks and 3,050 g, respectively. Prenatal ultrasonography and postnatal radiography, lung ultrasonography, and chest computed tomography (CT) showed inconsistent findings. Chest CT showed superior sensitivity (100%) and positive predictive value (90%). Among the 66 patients, 59 had postnatally confirmed CPAM, three had pulmonary sequestration, one had cystic teratoma, and one had a normal lung. Of the 59 patients with CPAM, 21 (35%; mean age, 23.4 months) underwent surgery, including 15 who underwent video-assisted thoracoscopy. Twenty-five and 12 patients exhibited respiratory symptoms at birth and during infancy, respectively. Apgar scores and mediastinal shift on radiography were significantly associated with respiratory symptoms at birth. However, none of the factors could predict respiratory symptoms during infancy. Conclusion: Radiography or ultrasonography combined with chest CT can confirm an unclear or inconsistent lesion. Apgar scores and mediastinal shift on radiography can predict respiratory symptoms at birth. However, symptoms during infancy are not associated with prenatal and postnatal factors. Chest CT combined with periodic symptom monitoring is important for diagnosing and managing patients with prenatally diagnosed CPAM and to guide appropriate timing of surgery.
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등록된 정보가 없습니다.
참고문헌 (26)
참고문헌 신청
Kulwa E / 2005 / Congenital cystic adenomatoid malformation in the fetus: a hypothesis of its development / Fetal Diagn Ther 20:472~474
Laje P / 2008 / Postnatal management and outcome of prenatally diagnosed lung lesions / Prenat Diagn 28:612~618
서영은 / 2013 / 조기수술이 필요한 폐 선천성 낭포성 샘 모양 기형아의 특성과 수술 전 중재적 시술 / Neonatal medicine 20(1):81~89
Stanton M. / 2015 / The argument for a non-operative approach to asymptomatic lung lesions / Semin Pediatr Surg 24:183~186
Stocker JT / 1977 / Congenital cystic adenomatoid malformation of the lung. Classification and morphologic spectrum / Hum Pathol 8:155~171
Laje P / 2008 / Postnatal management and outcome of prenatally diagnosed lung lesions / Prenat Diagn 28:612~618
서영은 / 2013 / 조기수술이 필요한 폐 선천성 낭포성 샘 모양 기형아의 특성과 수술 전 중재적 시술 / Neonatal medicine 20(1):81~89
Stanton M. / 2015 / The argument for a non-operative approach to asymptomatic lung lesions / Semin Pediatr Surg 24:183~186
Stocker JT / 1977 / Congenital cystic adenomatoid malformation of the lung. Classification and morphologic spectrum / Hum Pathol 8:155~171
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