지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 179 - 191 (13page)
이용수
초록· 키워드
오류제보하기
Background: Mortality rates associated with sepsis have increased progressively in Korea, but domestic epidemiologic data remain limited. The objective of this study was to investigate the characteristics, management and clinical outcomes of sepsis patients in Korea. Methods: This study is a multicenter retrospective cohort study. A total of 64,021 adult patients who visited an emergency department (ED) within one of the 19 participating hospitals during a 1-month period were screened for eligibility. Among these, patients diagnosed with sepsis based on the third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) were included in the study. Results: Using the Sepsis-3 criteria, 977 sepsis patients were identified, among which 36.5% presented with septic shock. The respiratory system (61.8%) was the most common site of infection. The pathogen involved was identified in 444 patients (45.5%) and multi-drug resistance (MDR) pathogens were isolated in 171 patients. Empiric antibiotic therapy was appropriate in 68.6% of patients, but the appropriateness was significantly reduced in infections associated with MDR pathogens as compared with non-MDR pathogens (58.8% vs. 76.0%, P<0.001). Hospital mortality was 43.2% and 18.5% in sepsis patients with and without shock, respectively. Of the 703 patients who survived to discharge, 61.5% were discharged to home and 38.6% were transferred to other hospitals or facilities. Conclusions: This study found the prevalence of sepsis in adult patients visiting an ED in Korea was 1.5% (15.2/1,000 patients). Patients with sepsis, especially septic shock, had a high mortality and were often referred to step-down centers after acute and critical care.
목차
등록된 정보가 없습니다.
참고문헌 (23)
참고문헌 신청
Fleischmann C / 2016 / Assessment of global incidence and mortality of hospital-treated sepsis : current estimates and limitations / Am J Respir Crit Care Med 193:259~272
Iwashyna TJ / 2010 / Long-term cognitive impairment and functional disability among survivors of severe sepsis / JAMA 304:1787~1794
Reinhart K / 2017 / Recognizing sepsis as a global health priority : a WHO resolution / N Engl J Med 377:414~417
Vincent JL / 2014 / Assessment of the worldwide burden of critical illness : the intensive care over nations(ICON)audit / Lancet Respir Med 2:380~386
Kaukonen KM / 2014 / Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000-2012 / JAMA 311:1308~1316
Iwashyna TJ / 2010 / Long-term cognitive impairment and functional disability among survivors of severe sepsis / JAMA 304:1787~1794
Reinhart K / 2017 / Recognizing sepsis as a global health priority : a WHO resolution / N Engl J Med 377:414~417
Vincent JL / 2014 / Assessment of the worldwide burden of critical illness : the intensive care over nations(ICON)audit / Lancet Respir Med 2:380~386
Kaukonen KM / 2014 / Mortality related to severe sepsis and septic shock among critically ill patients in Australia and New Zealand, 2000-2012 / JAMA 311:1308~1316
함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
Antibiogram of Multidrug-Resistant Bacteria Based on Sepsis Onset Location in Korea: A Multicenter Cohort Study
Journal of Korean Medical Science
2023 .03
-
Korean Registry for Improving Sepsis Survival (KISS): Protocol for a Multicenter Cohort of Adult Patients with Sepsis or Septic Shock
Infection and Chemotherapy
2020 .01
-
Sepsis: Early Recognition and Optimized Treatment
Tuberculosis and Respiratory Diseases
2019 .01
-
Mortality difference between early-identified sepsis and late-identified sepsis
Clinical and Experimental Emergency Medicine
2020 .01
-
Mortality of adult patients due to sepsis and septic shock in South Korea: a systematic review and metaanalysis
Clinical and Experimental Emergency Medicine
2023 .06
-
Biomarkers and Associated Immune Mechanisms for Early Detection and Therapeutic Management of Sepsis
Immune Network
2020 .06
-
패혈증 환자에서 패혈쇼크의 발생을 예측하기 위한 프로칼시토닌의 효용성
대한응급의학회지
2023 .06
-
Application of Sepsis-3 Criteria to Korean Patients with Critical Illnesses
Acute and Critical Care
2019 .01
-
Sepsis-induced cardiomyopathy is associated with higher mortality rates in patients with sepsis
Acute and Critical Care
2021 .08
-
Risk Factors of Sepsis and Factors Influencing the Decision to Perform Emergency Drainage in Obstructive Acute Pyelonephritis Secondary to Urinary Calculi
Urogenital Tract Infection
2017 .01
-
An Update on Sepsis Biomarkers
Infection and Chemotherapy
2020 .01
-
Pre-Sepsis Length of Hospital Stay and Mortality: A Nationwide Multicenter Cohort Study
Journal of Korean Medical Science
2024 .03
-
Sepsis and Acute Respiratory Distress Syndrome: Recent Update
Tuberculosis and Respiratory Diseases
2016 .01
-
패혈증의 새 정의에 대한 논쟁
대한내과학회지
2017 .01
-
Usefulness of ischemia-modified albumin in the diagnosis of sepsis/septic shock in the emergency department
Clinical and Experimental Emergency Medicine
2020 .01
-
Comparison of Blood Culture Parameters between 2 and 10 mL Aerobic Bottles from Patients with Sepsis
Annals of Clinical Microbiology
2021 .09
-
Cancer Patients Are at High Risk of Mortality if Presenting with Sepsis at an Emergency Department
Asian Pacific journal of cancer prevention : APJCP
2016 .01
-
The DEXA-SEPSIS study protocol: a phase II randomized double-blinded controlled trial of the effect of early dexamethasone in high-risk sepsis patients
Clinical and Experimental Emergency Medicine
2022 .09
-
Significance of Biomarkers as a Predictive Factor for Post-Traumatic Sepsis
Journal of trauma and injury : JTI
2018 .01
-
Sepsis diagnosis and treatment using nanomaterials
Biomedical Engineering Letters (BMEL)
2021 .08
이 논문의 저자 정보
최근 본 자료
댓글(0)
0