지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background : Intravenous fat emulsions (IVFE) can promote pathogenic organisms to proliferate. Therefore, many guidelines recommend changing intravenous infusion sets for IVFE administration every 24 or 12 hours. In this study, we evaluated the effect of IVFE hang time on central line-associated bloodstream infection (CLABSI) rates and analyzed risk factors of CLABSI in a single center neonatal intensive care unit (NICU). Methods : This is a retrospective study of NICU patients who were prescribed SMOFlipid 20% 100mL emulsion from 1 January 2017 to 30 June 2018. We divided the patients into two groups, based on IVFE hang time; 24 hours group (n=247) and 12 hours group (n=85). Results : Demographic characteristics were similar between the two groups; except birth weight. Duration of hospital stay and catheter dwell time was longer in the 24 hours group. There was no significant difference in CLABSI rate between the two groups (1.60 vs. 1.52 per 1,000 catheter days in the 24 hours vs. 12 hours groups). Risk factor analysis indicated that prolonged hospitalization (≥80 days, p=0.048), longer catheter dwell time (≥35 days, p=0.001), duration of IVFE (≥14 days, p=0.034) and duration of total parenteral nutrition (≥7 days, p=0.031) were statically significant in univariable analysis. On multivariable analysis, catheter dwell time (odds ratio 10.73; 95% confidential interval 1.695- 67.926; p=0.012) was independently associated with the occurrence of CLABSI. Conclusions : Shortening IVFE hang time from 24 hours to 12 hours did not alter CLABSI rate, and risk factor of CLABSI was catheter dwell time.
목차
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참고문헌 (15)
참고문헌 신청
Sacks GS / 2002 / Does Lipid Hang Time Make a Difference? Time Is of the Essence / Nutr Clin Pract 17(5):284~290
Dedonato BM / 2013 / Microbial growth in neonatal intravenous fat emulsion administered over 12 versus 24hours / J Pediatr Pharmacol Ther 18(4):298~302
Gilbert M / 1986 / Microbial growth patterns in a total parenteral nutrition formulation containing lipid emulsion / JPEN J Parenter Enteral Nutr 10(5):494~497
Gorski L / 2016 / Infusion Therapy Standards of Practice / J Infus Nurs 39(1S):S1~S159
Ayers P / 2014 / A.S.P. E.N. Parenteral Nutrition Safety Consensus Recommendations / JPEN J Parenter Enteral Nutr 38(3):296~333
Dedonato BM / 2013 / Microbial growth in neonatal intravenous fat emulsion administered over 12 versus 24hours / J Pediatr Pharmacol Ther 18(4):298~302
Gilbert M / 1986 / Microbial growth patterns in a total parenteral nutrition formulation containing lipid emulsion / JPEN J Parenter Enteral Nutr 10(5):494~497
Gorski L / 2016 / Infusion Therapy Standards of Practice / J Infus Nurs 39(1S):S1~S159
Ayers P / 2014 / A.S.P. E.N. Parenteral Nutrition Safety Consensus Recommendations / JPEN J Parenter Enteral Nutr 38(3):296~333
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