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학제간연구 과학기술학 뇌인지과학 기술정책 기타 복합학

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논문 기본 정보

자료유형
학술저널
저자정보
저널정보
대한한방안이비인후피부과학회 한방안이비인후피부과학회지 한방안이비인후피부과학회지 제32권 제2호
발행연도
2019.1
수록면
24 - 58 (35page)

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초록· 키워드

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Objectives : The purpose of this study is to confirm the Efficacy and Safety of “Functional cosmetics containing Humulus japonicus Extract” on dry skin due to mild atopic dermatitis. Methods : A total of 48 patients who visited Semyung Oriental Medical Center from March 20th, 2018 to July 5th, 2018 were included in the study. In this study, the patients were treated with Functional cosmetics containing Humulus japonicus Extract and positive control group. For 6 weeks of gross examination, instrumental assessment were made before and after the study to evaluate how well the products for treatment group with positive control products for control group in recovering the dry skin barriers by mild atopic dermatitis. Results : 1. In the primary endpoint, Skin Hydration showed a statistically significant increase and Transepidermal Water Loss(TEWL) showed a statistically significant decrease in treatment group between Baseline and 6 weeks. 2. In the secondary endpoint, Skin Hydration showed a statistically significant increase in treatment group between Baseline and 3 weeks, but TEWL showed no statistical significance. 3. In the secondary endpoint, Skin Hydration showed a statistically significant increase in treatment group between 3 weeks and 6 weeks, but TEWL showed no statistical significance. 4. In the secondary endpoint, Change of Skin Hydration and TEWL between treatment and control group showed a statistical significance in 6 weeks. 5. In the secondary endpoint, Change of Skin Hydration of 1㎝ below the medial aspect of the elbow between treatment and control group showed a statistical significance in 3 weeks. 6. In the secondary endpoint, Change of Skin Hydration between treatment and control group showed a statistical significance in 3 weeks and 6 weeks except Center between the medial aspect of the elbow and the wrist in 3 weeks, and Change of TEWL between treatment and control group showed a statistical significance in 6 weeks. 7. To evaluate the safety of the products for the human body, Adverse events, EASI Score, Itching Symptoms Assessment, vital sign check were conducted; There were no severe adverse events during this study. And both experimental group and control group showed no abnormal level. Therefore, it is suggested that products, if used for certain period, should be safe for the human body. Conclusions : According to the above experiments, it is suggested that “Functional cosmetics containing Humulus japonicus Extract” should be effective for dry skin due to mild atopic dermatitis.

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참고문헌 (30)

참고문헌 신청
Kim HJ / 2016 / Refractory Atopic Dermatitis / 2016 KAAACI Annual Spring Congress: New Paradigms in Allergic Diseases :255~262 google schola Hatakka K / 2009 / Allergy in day care children : prevalence and environmental risk factors / Acta Paediatr 98(5):817~822 google schola De Bruin Weller MS / 2012 / Evaluation of the child with atopic dermatitis / Clin Exp Allergy 42(3):352~362 google schola Maheswaran D / 2014 / Exposure to Beta-(1, 3)-D-glucan in house dust at age 7-10 is associated with airway hyperresponsiveness and atopic asthma by age 11-14 / PLoS One 9(6):1~11 google schola Ahn SK / 2015 / Common Skin Disease / Jeong Woo Medical Book :75~111 google schola

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