지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2019.1
- 수록면
- 399 - 405 (7page)
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초록· 키워드
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Purpose: In the present study, the volume of hard exudates (HEs) was quantitatively measured using optical coherencetomography (OCT) and the agreement and correlation with area of HEs in fundus photography wereanalyzed. Methods: The medical records of patients with diabetic macular edema who underwent focal laser treatmentand were followed up more than 3 months were retrospectively evaluated. An automated customized programdesigned for measuring HE volume was used. The HEs in each OCT B-scan binary image were measuredusing 512 × 128 pixels, 6 mm × 6 mm OCT cube scans. The volume was measured by summing the segmentedHEs in each 128 B-scan image. The area was measured in 6 mm x 6 mm fundus photography. The volumeand area were measured before and 3 months after the treatment. The agreement of increase and decreasein HEs, and the correlation of volume and area of HEs were analyzed. Results: A total of 35 patients (39 eyes) were included in the study. The volume was significantly reduced from0.07978 to 0.02565 mm3 at 3 months (p < 0.001). The area was also significantly reduced from 15.35 to 8.60mm2 at 3 months (p < 0.001). The volume was decreased in 34 eyes and increased in 5 eyes. The area wasdecreased in 37 eyes and increased in 2 eyes. A significant correlation between volume and area was found(p < 0.001) as well as agreement between increase and decrease in volume and area. Conclusions: In the 3-dimensional quantitative volumetric analysis, the volume and area of HEs were correlatedand the direction of increase and decrease was concordant. Considering the distribution of HEs in multiplelayers of the retina, volumetric analysis could be considered a substitute for the analysis of HE area.
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참고문헌 (21)
참고문헌 신청
Schachat AP / 2017 / Ryan’s retina: volume 2 medical retina / Elsevier :1038
Klein R / 1984 / The Wisconsin epidemiologic study of diabetic retinopathy. IV. Diabetic macular edema / Ophthalmology 91:1464~1474
Csaky KG / 2008 / Report from the NEI/FDA Ophthalmic Clinical Trial Design and Endpoints Symposium / Invest Ophthalmol Vis Sci 49:479~489
Diabetic Retinopathy Clinical Research Network / 2007 / Relationship between optical coherence tomography-measured central retinal thickness and visual acuity in diabetic macular edema / Ophthalmology 114:525~536
1991 / Grading diabetic retinopathy from stereoscopic color fundus photographs: an extension of the modified Airlie House classification. ETDRS report number 10. Early Treatment Diabetic Retinopathy Study Research Group / Ophthalmology 98(5 Suppl):786~806
Klein R / 1984 / The Wisconsin epidemiologic study of diabetic retinopathy. IV. Diabetic macular edema / Ophthalmology 91:1464~1474
Csaky KG / 2008 / Report from the NEI/FDA Ophthalmic Clinical Trial Design and Endpoints Symposium / Invest Ophthalmol Vis Sci 49:479~489
Diabetic Retinopathy Clinical Research Network / 2007 / Relationship between optical coherence tomography-measured central retinal thickness and visual acuity in diabetic macular edema / Ophthalmology 114:525~536
1991 / Grading diabetic retinopathy from stereoscopic color fundus photographs: an extension of the modified Airlie House classification. ETDRS report number 10. Early Treatment Diabetic Retinopathy Study Research Group / Ophthalmology 98(5 Suppl):786~806
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