지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
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Background: Exposure and sensitization to fungal allergens can evoke the development and worsen allergic diseases. Many patients with allergies show multiple positive reactions to different allergens. Objective: The purpose of this study was to analyze the relationship between fungal allergens that are mostly found in South Korea and other positive reactions to the allergens of the multiple allergosorbent simultaneous test chemiluminescent assay (MAST-CLA). Methods: We enrolled 1,040 (588 men, 452 women) patients who showed positive reactions to three fungi, namely, Alternaria alternata, Aspergillus fumigatus, and Cladosporium herbarum, using MAST-CLA at Daegu Catholic University Medical Center from January 2010 to July 2017. The epidemiology and relationship between positive reactions to multiple fungal allergens and positive reactions to the allergens of the MAST-CLA were investigated. Results: A. alternata was the most common fungal species, followed by C. herbarum and A. fumigatus (78.8% vs. 52.1% vs. 20.1%). Patients who showed positive reactions to all fungal allergens had 4.97 other antigens on average. Statistically significant results were obtained when comparing positive reactions to all fungal allergens to other allergens (Spearman correlation coefficient = 0.129, p < 0.05). Conclusion: Patients should be educated on allergic diseases caused by other antigens if they are sensitized to fungal antigens.
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참고문헌 (43)
참고문헌 신청
Lim HS / 2001 / Allergen pattern using MAST CLA test in Korean pediatric patients / Korean J Clin Pathol 21:292~297
김현수 / 2005 / MAST CLA 알레르기 검사에서 동시 양성 알레르겐의 분석 / Annals of Laboratory Medicine 25(6):448~456
Ezeamuzie CI / 2000 / IgE-mediated sensitization to mould allergens among patients with allergic respiratory diseases in a desert environment / Int Arch Allergy Immunol 121:300~307
Nolles G / 2001 / Prevalence of immunoglobulin E for fungi in atopic children / Clin Exp Allergy 31:1564~1570
D'Amato G / 1997 / Evaluation of the prevalence of skin prick test positivity to Alternaria and Cladosporium in patients with suspected respiratory allergy. A European multicenter study promoted by the Subcommittee on Aerobiology and Environmental Aspects of Inhalant Allergens of the European Academy of Allergology and Clinical Immunology / Allergy 52:711~716
김현수 / 2005 / MAST CLA 알레르기 검사에서 동시 양성 알레르겐의 분석 / Annals of Laboratory Medicine 25(6):448~456
Ezeamuzie CI / 2000 / IgE-mediated sensitization to mould allergens among patients with allergic respiratory diseases in a desert environment / Int Arch Allergy Immunol 121:300~307
Nolles G / 2001 / Prevalence of immunoglobulin E for fungi in atopic children / Clin Exp Allergy 31:1564~1570
D'Amato G / 1997 / Evaluation of the prevalence of skin prick test positivity to Alternaria and Cladosporium in patients with suspected respiratory allergy. A European multicenter study promoted by the Subcommittee on Aerobiology and Environmental Aspects of Inhalant Allergens of the European Academy of Allergology and Clinical Immunology / Allergy 52:711~716
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