지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 저널정보
- 대한소아알레르기호흡기학회 Allergy Asthma & Respiratory Diseases Allergy Asthma & Respiratory Diseases 제7권 제4호
- 발행연도
- 2019.1
- 수록면
- 173 - 178 (6page)
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초록· 키워드
오류제보하기
Kawasaki disease (KD) is a systemic vasculitis and the most common cause of acquired heart disease among preschool-aged children. Asthma is one of the most common chronic illness of childhood. There is increasing interest in the potential link between inflammatory diseases and allergic diseases, and there is increasing epidemiologic evidence for an association of KD and allergic disease. In regards to asthma, 9 studies have been reported about its association with KD; 5 of them showed positive associations between these 2 diseases, while 4 of them showed no association. There are some possible underlying mechanisms for this association. The serum IgE levels are found to be increased and there is a Th2-predominant immune response in KD. These are common findings of asthma. Human leukocyte antigen-G/regT cells and SMAD3/transforming growth factor-beta might also be involved in the pathogenesis of both diseases. Asthma may increase susceptibility to KD and tends to lead to immune dysregulation. Clinician’s recognition of the increased risks of KD and other asthma-related comorbidities among patients with asthma may enable early identification and intervention. The early identification and management of comorbidities may ultimately reduce the economic and social burden of these chronic conditions.
목차
등록된 정보가 없습니다.
참고문헌 (44)
참고문헌 신청
Kim GB / 2017 / Epidemiology and clinical features of Kawasaki disease in South Korea, 2012-2014. / Pediatr Infect Dis J 36:482~485
Kato H / 1996 / Long-term consequences of Kawasaki disease. A 10- to 21-year follow-up study of 594 patients / Circulation 94:1379~1385
Dajani AS / 1993 / Diagnosis and therapy of Kawasaki disease in children / Circulation 87:1776~1780
Newburger JW / 2004 / Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association / Circulation 110:2747~2771
Chang RK / 2003 / The incidence of Kawasaki disease in the United States did not increase between 1988 and 1997 / Pediatrics 111(5 Pt 1):1124~1125
Kato H / 1996 / Long-term consequences of Kawasaki disease. A 10- to 21-year follow-up study of 594 patients / Circulation 94:1379~1385
Dajani AS / 1993 / Diagnosis and therapy of Kawasaki disease in children / Circulation 87:1776~1780
Newburger JW / 2004 / Diagnosis, treatment, and long-term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association / Circulation 110:2747~2771
Chang RK / 2003 / The incidence of Kawasaki disease in the United States did not increase between 1988 and 1997 / Pediatrics 111(5 Pt 1):1124~1125
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