지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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The present study is aimed to assess the effect of antimicrobial photodynamic therapy (aPDT) on Streptococcus mutans biofilm through teeth whitening light emitting diode (LED). Planktonic and dynamic biofilm state cultures of S. mutans were used. Erythrosine 20 μM/L was used as the photosensitizer. Irradiation was performed by exposing cultures to clinic and homecare whitening LEDs for 15 minutes. The viability was measured through Colony Forming Unit counts and confocal laser scanning microscopy. aPDT using whitening LEDs and erythrosine significantly decreased the CFU count of S. mutans compared to that in the control group. Dynamic biofilm group showed more resistant features to aPDT compared with planktonic state. Clinic and homecare whitening LED device showed similar antimicrobial effect. The whitening LED, which could irradiate the entire oral arch, showed a significant photodynamic effect on cariogenic S. mutans biofilm. aPDT mediated by erythrosine and LEDs used for teeth whitening exhibited promising antimicrobial activity.
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참고문헌 (27)
참고문헌 신청
Bowen WH / 2002 / Do we need to be concerned about dental caries in the coming millennium? / Crit Rev Oral Biol Med 13:126~131
Bowen WH / 2011 / Biology of Streptococcus mutans-derived glucosyltransferases : role in extracellular matrix formation of cariogenic biofilms / Caries Res 45:69~86
Marsh PD / 2010 / Controlling the oral biofilm with antimicrobials / J Dent 38:S11~15
Van Straten D / 2017 / Oncologic photodynamic therapy : Basic principles, current clinical status and future directions / Cancers(Basel) 9:E19
Dolmans DE / 2003 / Photodynamic therapy for cancer / Nat Rev Cancer 3:380~387
Bowen WH / 2011 / Biology of Streptococcus mutans-derived glucosyltransferases : role in extracellular matrix formation of cariogenic biofilms / Caries Res 45:69~86
Marsh PD / 2010 / Controlling the oral biofilm with antimicrobials / J Dent 38:S11~15
Van Straten D / 2017 / Oncologic photodynamic therapy : Basic principles, current clinical status and future directions / Cancers(Basel) 9:E19
Dolmans DE / 2003 / Photodynamic therapy for cancer / Nat Rev Cancer 3:380~387
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