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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 608 - 612 (5page)
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초록· 키워드
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Objective Disgust has been propounded as a potential etiological factor in certain sexual dysfunctions such as vaginismus. Studies reports that insular cortex is activated as a response to disgust. The present study aimed to investigate the predictive role of metabolites in insular cortex in response to group therapy among vaginismus patients.Methods Study sample consisted of 51 vaginismus patients attended an ambulatory group therapy, of whom 26 benefited from 8-week group therapy and 25 were unresponsive to group therapy. All of the patients underwent H magnetic resonance spectroscopy (H-MRS), and insular cortex N-acetyl aspartate (NAA), Creatinine (Cr), Glutamine (Gln), Glutathione (GSH), Choline (Cho), Myo-inositol (mIns), Glutamate (Glu) and Lactate (Lac) concentrations were compared between the groups.Results Comparing insular cortex metabolite concentrations between the groups, Cho was statistically significantly higher (p=0.005) but mIns was significantly lower (p=0.001) in the unresponsive to group therapy group.Conclusion MR spectroscopy findings of the present study indicated significant metabolic changes such as increased Cho/Cr ratio and decreased mIns/Cr ratio in the insular cortex of vaginismus patients who were unresponsive to group therapy. Our results support the studies suggesting that disgust is an important emotion in vaginismus patients and also that insula plays a role in the neurobiology of disgust.
목차
등록된 정보가 없습니다.
참고문헌 (25)
참고문헌 신청
Kadir ZS / 2018 / The neurobiology and psychiatric perspective of vaginismus : linking the pharmacological and psycho-social interventions / Curr Drug Targets 19:916~926
American Psychiatric Association / 2013 / Diagnostic and Statistical Manual of Mental Disorders / American Psychiatric Publication
Tybur JM / 2013 / Disgust : evolved function and structure / Psychol Rev 120:65~84
Curtis V / 2011 / Disgust as an adaptive system for disease avoidance behavior / Philos Trans R Soc B 366:389~401
deJong PJ / 2010 / Disgust and sexual problems-theoretical conceptualization and case illustrations / Int J Cogn Ther 3:23~39
American Psychiatric Association / 2013 / Diagnostic and Statistical Manual of Mental Disorders / American Psychiatric Publication
Tybur JM / 2013 / Disgust : evolved function and structure / Psychol Rev 120:65~84
Curtis V / 2011 / Disgust as an adaptive system for disease avoidance behavior / Philos Trans R Soc B 366:389~401
deJong PJ / 2010 / Disgust and sexual problems-theoretical conceptualization and case illustrations / Int J Cogn Ther 3:23~39
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