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논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 59 - 65 (7page)
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Abstract Hyperuricemia, which has been considered as a cause of gout and nephrolithiasis has recently been suggested to be associated with hypertension, coronary heart disease, heart failure, atrial fibrillation, insulin resistance, and nonalcoholic fatty liver disease. Several clinical and experimental studies have supported uric acid (UA) as an independent risk factor for predicting disease development along with the traditional risk factors. The mechanism by which UA causes cardiometabolic disease has not been fully elucidated to date; however, it has been explained by several hypotheses such as oxidative stress, reduced nitric oxide bioavailability, inflammation, endothelial dysfunction, and so on. Although evidence of the preventive and therapeutic effects of UA lowering therapy on cardiometabolic diseases is still insufficient, it is expected to be considered as a new treatment strategy for such diseases through additional, carefully designed, large-scale clinical studies.
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참고문헌 (111)
참고문헌 신청
El Ridi R / 2017 / Physiological functions and pathogenic potential of uric acid : a review / J Adv Res 8:487~493
Chaudhary K / 2013 / Uric acid-key ingredient in the recipe for cardiorenal metabolic syndrome / Cardiorenal Med 3:208~220
Choi HK / 2004 / Purine-rich foods, dairy and protein intake, and the risk of gout in men / N Engl J Med 350:1093~1103
Faller J / 1982 / Ethanol-induced hyperuricemia : evidence for increased urate production by activation of adenine nucleotide turnover / N Engl J Med 307:1598~1602
Perez-Pozo SE / 2010 / Excessive fructose intake induces the features of metabolic syndrome in healthy adult men : role of uric acid in the hypertensive response / Int J Obes 34:454~461
Chaudhary K / 2013 / Uric acid-key ingredient in the recipe for cardiorenal metabolic syndrome / Cardiorenal Med 3:208~220
Choi HK / 2004 / Purine-rich foods, dairy and protein intake, and the risk of gout in men / N Engl J Med 350:1093~1103
Faller J / 1982 / Ethanol-induced hyperuricemia : evidence for increased urate production by activation of adenine nucleotide turnover / N Engl J Med 307:1598~1602
Perez-Pozo SE / 2010 / Excessive fructose intake induces the features of metabolic syndrome in healthy adult men : role of uric acid in the hypertensive response / Int J Obes 34:454~461
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