Risk Factors for Duodenal Stump Leakage after Laparoscopic Gastrectomy for Gastric Cancer

Ping Chen; Lihu Gu; Kang Zhang; Zefeng Shen; Xianfa Wang; Hepan Zhu; Junhai Pan; Xin Zhong; Parikshit Asutosh Khadaroo

추천

검색

자료유형: 학술저널

저자정보: Ping Chen Lihu Gu Kang Zhang Zefeng Shen Xianfa Wang Hepan Zhu Junhai Pan Xin Zhong Parikshit Asutosh Khadaroo

저널정보: 대한위암학회 Journal of Gastric Cancer Journal of Gastric Cancer 제20권 제1호

발행연도: 2020.1

수록면: 81 - 94 (14page)

이용수

📌

연구주제

📖

연구배경

🔬

연구방법

🏆

연구결과

초록· 키워드

오류제보하기

Purpose Duodenal stump leakage (DSL) is a potentially fatal complication that can occur after gastrectomy, but its underlying risk factors are unclear. This study aimed to investigate the risk factors and management of DSL after laparoscopic radical gastrectomy for gastric cancer (GC). Materials and Methods Relevant data were collected from several prospective databases to retrospectively analyze the data of GC patients who underwent Billroth II (B-II) or Roux-en-Y (R-Y) reconstruction after laparoscopic gastrectomy from 2 institutions (Sir Run Run Shaw Hospital, Zhejiang University School of Medicine, and HwaMei Hospital, University of Chinese Academy of Sciences). The DSL risk factors were analyzed using univariate and multivariate analysis regression. Results A total of 810 patients were eligible for our analysis (426 with R-Y, 384 with B-II with Braun). Eleven patients had DSL (1.36%). Body mass index (BMI), elevated preoperative C-reactive protein (CRP) level, and unreinforced duodenal stump were the independent risk factors for DSL. DSL was diagnosed in 2–12 days, with a median of 8 days. Seven patients received conservative treatment, 3 patients received puncture treatment, and only 1 patient required reoperation. All patients recovered successfully after treatment. Conclusions The risk factors of DSL were BMI ≥24 kg/m2, elevated preoperative CRP level, and unreinforced duodenal stump. Nonsurgical treatments for DSL are preferred.

참고문헌 (42)

참고문헌 신청

Bray F / 2018 / Global cancer statistics 2018 : GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries / CA Cancer J Clin 68:394~424

Sasako M / 2008 / D2 lymphadenectomy alone or with para-aortic nodal dissection for gastric cancer / N Engl J Med 359:453~462

Lee CM / 2017 / Sentinel node mapping using a fluorescent dye and visible light during laparoscopic gastrectomy for early gastric cancer : result of a prospective study from a single institute / Ann Surg 265:766~773

Jung DH / 2017 / Laparoscopic proximal gastrectomy with double tract reconstruction is superior to laparoscopic total gastrectomy for proximal early gastric cancer / Surg Endosc 31:3961~3969

Yu J / 2019 / Effect of laparoscopic vs open distal gastrectomy on 3-year disease-free survival in patients with locally advanced gastric cancer : the CLASS-01 randomized clinical trial / JAMA 321:1983~1992

함께 읽어보면 좋을 논문

논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!