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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 248 - 256 (9page)
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초록· 키워드
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Background/Aims: The natural history of spontaneous decrease in the size of pancreatic cystic lesions (PCLs) without high-risk stigmata is under investigation. This study aimed to investigate the timing of spontaneous decrease in the size of PCLs without high-risk stigmata and to identify the characteristics associated with their complete resolution. Methods: From 2000 to 2016, patients with spontaneous decreases in PCL size on computed tomography (CT) and/or magnetic resonance imaging (MRI) who had at least 1 year of follow-up were evaluated retrospectively. Results: A total of 78 patients underwent follow-up for an average of 55.7 months. Most patients were asymptomatic, and 35 (37.2%) showed complete resolution. The initial mean PCL size was 1.6±0.9 cm (range, 0.5 to 5.6 cm). The average time to initial decrease in size and complete resolution of PCLs were 32.1 and 41.5 months, respectively. Compared with PCLs that completely resolved, presence of underlying malignancy was associated with partial resolution of PCLs in multivariable analysis (hazard ratio, 0.51; 95% confidence interval, 0.32 to 0.81; p=0.005). Endoscopic ultrasound (EUS) identified detailed findings, especially the presence of septum (p<0.001), calcification (p=0.015) and lobulation (p=0.001) that were not found on CT/MRI. Conclusions: Asymptomatic small PCLs without high-risk stigmata can naturally decrease in size at approximately 3 years, and complete resolution can be expected in the absence of underlying malignancy. Regular follow-up of approximately 3 years with EUS may be a reasonable and safe alternative when planning the initial treatment of small PCLs without high-risk stigmata.
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등록된 정보가 없습니다.
참고문헌 (21)
참고문헌 신청
Laffan TA / 2008 / Prevalence of unsuspected pancreatic cysts on MDCT / AJR Am J Roentgenol 191:802~807
de Jong K / 2012 / Disappointing interobserver agreement among radiologists for a classifying diagnosis of pancreatic cysts using magnetic resonance imaging / Pancreas 41:278~282
Vege SS / 2015 / American gastroenterological association institute guideline on the diagnosis and management of asymptomatic neoplastic pancreatic cysts / Gastroenterology 148:819~822
Lee KS / 2010 / Prevalence of incidental pancreatic cysts in the adult population on MR imaging / Am J Gastroenterol 105:2079~2084
Tanaka M / 2012 / International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas / Pancreatology 12:183~197
de Jong K / 2012 / Disappointing interobserver agreement among radiologists for a classifying diagnosis of pancreatic cysts using magnetic resonance imaging / Pancreas 41:278~282
Vege SS / 2015 / American gastroenterological association institute guideline on the diagnosis and management of asymptomatic neoplastic pancreatic cysts / Gastroenterology 148:819~822
Lee KS / 2010 / Prevalence of incidental pancreatic cysts in the adult population on MR imaging / Am J Gastroenterol 105:2079~2084
Tanaka M / 2012 / International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas / Pancreatology 12:183~197
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