지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
논문 기본 정보
- 자료유형
- 학술저널
- 저자정보
- 발행연도
- 2020.1
- 수록면
- 190 - 198 (9page)
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초록· 키워드
오류제보하기
Background/Aims: Patients treated with endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) are at risk of developing metachronous gastric cancer (MGC). The aim of this study was to evaluate the clinical outcomes of MGC after ESD for EGC between the re-ESD and surgery groups. Methods: In total, data from 1,510 patients who underwent ESD for EGC from January 2005 to May 2014 were retrospectively reviewed, and data from 112 patients with MGC were analyzed according to the type of treatment, namely, re-ESD and surgery. The clinicopathological factors affecting the subsequent treatment and outcomes of MGC were evaluated. Results: The median duration to the development of MGC was 47 months. In multivariate analysis, lower body mass index (BMI) (p=0.037) and multiplicity (p=0.014) of index cases were significantly associated with subsequent surgery for MGC. In cases of MGC, a diffuse or mixed-type Lauren classification (p=0.009), the depth of tumor mucosal invasion (p=0.001), and an upper stomach location (p=0.049) were associated with surgery. Overall survival was significantly shorter in the surgery group than in the re-ESD group after treatment for MGC (log-rank test, p=0.01). Conclusions: Lower BMI and multiplicity of index cancers were significantly associated with the surgical resection of MGC. Close follow-up is needed to minimize additional treatment for cases at high risk of advanced MGC after ESD for EGC.
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참고문헌 (30)
참고문헌 신청
Ferlay J / 2015 / Cancer incidence and mortality worldwide : sources, methods and major patterns in GLOBOCAN 2012 / Int J Cancer 136:E359~E386
Toshihiro Nishizawa / 2018 / Long-Term Outcomes of Using Endoscopic Submucosal Dissection to Treat Early Gastric Cancer / Gut and Liver 12(2):119~124
Asada K / 2015 / Demonstration of the usefulness of epigenetic cancer risk prediction by a multicentre prospective cohort study / Gut 64:388~396
Seiichiro Abe / 2018 / Metachronous Gastric Cancer Following Curative Endoscopic Resection of Early Gastric Cancer / Clinical Endoscopy 51(3):253~259
Abe S / 2015 / Long-term surveillance and treatment outcomes of metachronous gastric cancer occurring after curative endoscopic submucosal dissection / Endoscopy 47:1113~1118
Toshihiro Nishizawa / 2018 / Long-Term Outcomes of Using Endoscopic Submucosal Dissection to Treat Early Gastric Cancer / Gut and Liver 12(2):119~124
Asada K / 2015 / Demonstration of the usefulness of epigenetic cancer risk prediction by a multicentre prospective cohort study / Gut 64:388~396
Seiichiro Abe / 2018 / Metachronous Gastric Cancer Following Curative Endoscopic Resection of Early Gastric Cancer / Clinical Endoscopy 51(3):253~259
Abe S / 2015 / Long-term surveillance and treatment outcomes of metachronous gastric cancer occurring after curative endoscopic submucosal dissection / Endoscopy 47:1113~1118
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