지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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초록· 키워드
오류제보하기
A systematic search was conducted and relevant studies that evaluated the influence of osteoporosis medications (bisphosphonates [BPs], denosumab, selective estrogen receptor modulators [SERMs], recombinant human parathyroid hormone teriparatide [TPTD], and strontium ranelate [SrR]) on wrist, hip, and spine fracture healing, were selected. BPs administration did not influence fracture healing and clinical outcomes after distal radius fracture (DRF). Similar results were observed in hip fracture, but evidence is lacking for spine fracture. Denosumab did not delay the non-vertebral fractures healing in one well-designed study. No studies evaluated the effect of SERMs on fracture healing in humans. One study reported shorter fracture healing times in TPTD treated DRF patients, which was not clinically meaningful. In hip fracture, recent studies reported better pain and functional outcomes in TPTD treated patients. However, in spine fracture, recent studies found no significant differences in fracture stability between TPTD treated patients and controls. Evidence is lacking for SrR, but it did not influence wrist fracture healing in one study. In comparisons between TPTD and BPs, fracture healing and physical scores were not significantly different in hip fracture by 1 study. In spine fracture, controversy exists for the role of each medication to the fracture stability, but several studies reported that fracture site pain was better in TPTD treated patients than BPs treated patients. Considering no clinical data of negative fracture healing of the antiresorptive medication and the danger of subsequent fracture after initial osteoporotic fracture, there is no evidence to delay initiation of osteoporosis medications after fracture
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등록된 정보가 없습니다.
참고문헌 (55)
참고문헌 신청
Khosla S / 2017 / Addressing the crisis in the treatment of osteoporosis : A path forward / J Bone Miner Res 32:424~430
Nakayama A / 2016 / Evidence of effectiveness of a fracture liaison service to reduce the re-fracture rate / Osteoporos Int 27:873~879
Sietsema DL / 2018 / The effectiveness of a private orthopaedic practice-based osteoporosis management service to reduce the risk of subsequent fractures / J Bone Joint Surg Am 100:1819~1828
Qaseem A / 2008 / Pharmacologic treatment of low bone density or osteoporosis to prevent fractures : a clinical practice guideline from the American College of Physicians / Ann Intern Med 149:404~415
Russell RG / 2011 / Bisphosphonates : the first 40 years / Bone 49:2~19
Nakayama A / 2016 / Evidence of effectiveness of a fracture liaison service to reduce the re-fracture rate / Osteoporos Int 27:873~879
Sietsema DL / 2018 / The effectiveness of a private orthopaedic practice-based osteoporosis management service to reduce the risk of subsequent fractures / J Bone Joint Surg Am 100:1819~1828
Qaseem A / 2008 / Pharmacologic treatment of low bone density or osteoporosis to prevent fractures : a clinical practice guideline from the American College of Physicians / Ann Intern Med 149:404~415
Russell RG / 2011 / Bisphosphonates : the first 40 years / Bone 49:2~19
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