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논문 기본 정보

자료유형
학술저널
저자정보
문종모 (대전대학교 한의과대학 병리학교실) 김성훈 (대전대학교 한의과대학 병리학교실)
저널정보
대전대학교 한의학연구소 논문집 : 대전대학교 한의학연구소. 한의학편 논문집 : 대전대학교 한의학연구소. 한의학편 제4권 제2호
발행연도
1996.1
수록면
91 - 103 (13page)

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This study was performed to prove the clinical effects of Kyejibokryoung hwan(KBH), Jeodangtang(JDT), Kyejibokryounghwan & Jeo-dangtang(KJT) by way of experimental methods. The intravascular coagulation was induced by injection of endotoxin into the caudal vein of rats. And liquid extracts of Kyejibokryounghwan, Jeodangtang, Kyejibokryounghwan & Jeodang- tang were administerd orally to the rats. Then the number of platelets, concentration of fibrinogen, FDP(fibrin-fibrinogen degradation products), prothrombin time and PTT(partial thromboplastin time) were measured. The results were obtained as follows ; 1. The number of platelets was significantly increased in KBH and KJT-treated groups in comparison with the control group. 2. Fibrinogen was significantly increased in all sample groups as compared with the control group. 3. FDP was insignificantly decreased in all sample groups but have not significant. 4. Prothrombin time was significantly shortened in JDT and KJT-treated groups as compared with the control group. 5. PTT was significantly shortened in only KJT -treated groups as compared with the control group. From the above results, it was concluded that Kyejibokryounghwan, Jeodang tang, Kyejibokryounghwan & Jeodangtang can be applied effectively in the disease of thrombosis.

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