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- 대한약학회 대한약학회 학술대회 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
- 발행연도
- 2003.1
- 수록면
- 2,411 - 2,411 (1page)
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초록· 키워드
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Apio nucleosides whose 4'-hydroxymethyl group moves to 3'-position exhibit interesting biological activity such as antitumor or antiviral activity. On the other hand, neplanocin A and aristeromycin are the representative of the carbocyclic nucleosides and have been recognized as potent inhibitors of S-adenosylhomocysteine hydrolase. Based on these findings. it was of great interest to design apio analogues of neplanocin A and aristeromycin. (omitted)
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DESIGN, SYNTHESIS AND IN VITRO EVALUATION OF APIO ANALOGUE OF NEPLANOCIN A
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Straightforward synthesis of 4'${\alpha}$-C-hydroxymethyl branched novel carbocyclic nucleosides
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Synthesis of (-)-Neplanocin A Analogues as Potential Antiviral Agents
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Structure-activity Relationship Study of Fluoro-Neplanocin A as Potential Antiviral and Antitumor Agents
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Inactivation of S-Adenosylhomocysteine Hydrolase by Fluoro-neplanocin A
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Synthesis of Novel Carboacyclic Nucleosides with Vinyl Bromide Moiety as Open-chain Analogues of Neplanocin A
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Synthesis and Biological Evaluation of 9-[2-Fluoro-4-hydroxy-3-hydroxymethyl-2-butenyl]adenine and its Related Compounds as Open-chain Analogues of Neplanocin A
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Synthesis and Antiviral Activity of Fluoro-substituted Apio Dideoxyuncleoside
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Design and Synthesis of Apio Nucleosides with Exocyclic Methylene Substituent
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The first synthesis of 4' ${\alpha}$-C aryl branched carbocyclic nucleosides
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Asymmetric Synthesis of Amino-Substituted Apio Dideoxynucleosides as Potential Anti-HBV Agent
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Stereoselective synthesis of carbocyclic analogue of Nucleocidin
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Cyclopropyl Intermediate for Synthesis of Novel Carbocyclic Nucleosides, Potential Antiviral Agents
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1,4-위치에 측쇄를 가진 신규 뉴크레오사이드의 합성 및 항바이러스 약효검색
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Efficient syntheses of the versatile intermediates for the synthesis of D- and L- carbocyclic nucleosides
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The Cyclobutyl Intermediate for Synthesis of Novel Carbocyclic Nucleosides, Potential Antiviral Agents
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Stereoselective synthesis of novel 4'-hydroxy-carbocyclic nucleosides
대한약학회 학술대회
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High enantioselective synthesis of novel 3′ -C-methyl apio and thioapionucleosides:an asymmetric elaboration of a quaternary carbon by Claisen rearrangement
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C-뉴크레오사이드의 화학합성
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Synthesis and Antiviral Activity of Novel trans-2,2-Dimethyl Cyclopropyl Nucleosides
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