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학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
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연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
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Purpose: Small uterine cervical tumors are often undetected on MRI, and undetectable tumors are usually regarded as being in their early stages. The purpose of this study was to evaluate morphological factors determining MRI detectability of uterine cervical tumors by comparing detected and undetected tumors using high resolution MRI units.Materials and Methods: Sixth-six surgically proven uterine cervical cancer patients were included in this study. Using GE Signa 1.5T magnet (GE, USA), axial T1-weighted MR images and axial, sagittal, and coronal T2-weighted fast spin echo MR images were obtained with a 5mm thickness/2mm gap and a 512$\times$256 matrix size. The patients were divided into two groups, tumor-detected and tumor-undetected. Maximal tumor dimension, depth of stromal invasion, and horizontal tumor spread, measured during histopathological examinations, as well as pathological stages, were compared between the two groups.Results: In the tumor-detected group, the pathological stages were IB1 in 25, IB2 in 3, IIA in 10, and IIB in 5 patients; in the tumor-undetected group, the stages were IA1 in 8, IA2 in 2, and IB1 in 13 patients. Maximal tumor dimension, depth of stromal invasion, and horizontal tumor spread for tumor-detected and -undetected groups were 27.4(10-60)mm vs. 10.4(3-40)mm (p=0.077), 11.1(3-20)mm vs. 2.3(0-5)mm (p<0.001), and 26.6(8-60)mm vs. 10.4(3-40)mm (p=0.057), respectivelyConclusion: Of the criteria studied, depth of stromal invasion is the most important factor in determining tumor detectability on MRI. All tumors is which this depth was more than 5mm were thus detected; those which are undetected on high resolution MRI can be regarded as early-stage tumors (stage IB1)
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