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논문 기본 정보

자료유형
학술저널
저자정보
박종호 (한림대학교 의과대학부속 강남성심병원 진단방사선과)
저널정보
대한영상의학회 대한방사선의학회지 대한방사선의학회지 제38권 제4호
발행연도
1998.1
수록면
589 - 593 (5page)

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Purpose : To evaluate the size of the olfactory bulb using MRI in normal volunteers and anosmic or hyposmic patients without nasal diseases. Materials and methods : MRI was performed in 20 normal volunteers with a normal sense of smell, and in 15 anosmic or hyposmic patients without nasal disease but with abnormality in the olfactory function test. Coronal T1-weighted MRI was performed, with a section thickness of 3mm. The cross sectional area, width and height of the olfactory bulb were measured in multiple sequential images and the largest values of these were analysed. The difference in the size of the olfactory bulb between normal volunteers and anosmic or hyposmic patients was evaluated and Student's t test was used for statistical analysis. Results : In most cases, the olfactory bulb was demonstrated in three sequential coronal images; in normal volunteers, the largest cross sectional area, width and height were not significantly different between the right and left olfactory bulb. In 40olfactory bulbs(right, left) in 20 normal volunteers and 30 olfactory bulbs in 15 anosmic or hyposmic patients, the respective means of various measurements were as follows: 7.5mm$^2$ and 6.0mm$^2$ ; greatest width, 4.6mm and 3.8mm ; greatest height, 2.7mm and 2.0mm. For the largest cross-sectional area and greatest height, the difference in olfactory bulb size between normal volunteers and patients was statistically significant (P<0.01) but for the greatest width, the difference was not significant (P>0.05). Conclusion : The size of the olfactory bulb is significantly less in anosmic or hyposmic patients without nasal disease than in normal volunteers; in such patients, olfactory MRI could be a useful evaluative modality.

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