하부식도에서 발생한 GIST 1예

이상훈; 오창권; 이기석; 조영업; 김경래

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자료유형: 학술저널

저자정보: 이상훈 (인하대학교 의과대학 외과학교실) 오창권 (아주대학교 의과대학 외과학교실*) 이기석 (인하대학교 의과대학 외과학교실) 조영업 (인하대학교 의과대학 외과학교실) 김경래 (인하대학교 의과대학 외과학교실)

저널정보: 대한기관식도과학회 대한기관식도과학회지 대한기관식도과학회지 제9권 제1호

발행연도: 2003.1

수록면: 87 - 91 (5page)

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Currently gastrointestinal mesenchymal tumors are divided into three major categories: myogenic tumors(leiomyoma, leiomyosarcoma), neurogenic tumors (schwannomas) and neoplasms that belong to neither group, which are known by GIST(gastrointestinal stromal tumors). The stromal tumors are hetrogenous, so that they may show myogenic or neurogenic differentiation or both, or no differentiation at all in some patients. The best defining feature for GIST is their expression of KIT-protein(CD117). Leiomyomas are the most common mesenchymal tumor in esophagus. Esophageal GISTS are very rare in comparision to those of the stomach and intestine. Recently we experieneced one case of the esophageal GIST, so that we describe an esophageal GIST on immunohistochemical analysis. A 70 years old woman complained of dysphagia and nausea for 3 days. FGS showed a huge elevated lesion in lower esophagus 33cm distal to incisor, which was covered with normal mucosa. CT and UGI showed the intramural tumor of lower third of the esophagus. The distal esophagectomy and esophago-gastrostomy were performed. The tumor was located in lower third of esophagus and measured as $6{\times}3.7$cm in size. Immunohistochemically, it showed weakly positive CD117 and diffusely positive S-100. SMA, desmin, NES and chromogranin showed negative immune-reaction. The patient was followed for 15 month after operation. There was no recurrence.

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