지원사업
학술연구/단체지원/교육 등 연구자 활동을 지속하도록 DBpia가 지원하고 있어요.
커뮤니티
연구자들이 자신의 연구와 전문성을 널리 알리고, 새로운 협력의 기회를 만들 수 있는 네트워킹 공간이에요.
초록· 키워드
오류제보하기
New diamide chiral stationary phases of four systematically substituted optically active N-(N-benzoyl-L-amino acid)-anilide synthesized from L-valine, L-leucine, L-isoleucine, and L-phenylalanine were described. The behaviors of these diamides as optically active stationary phases for the separation of N-trifluoroacetyl-D,L-amino acids were examined with respect to separation factors(${\alpha}$) and thermodynamic properties of interaction. The separation of twelve N-trifluoroacetyl-D,L-amino acid isopropyl esters were improved by the order of N-(N-benzoyl-L-leucyl)-anilide>N-(N-benzoyl-L-isoleucyl)-anilide>N-(N-benzoyl-L-valyl)-anilide>N-(N-benzoyl-L-phenylalanyl)-anilide. Eight amino acid derivatives with non-polar R-group and threonine, serine, aspartic acid, and glutamic acid enantiomers were separated on N-(N-benzoyl-L-leucyl)-anilide as chiral stationary phase with good separation factor between 1.07-1.25. The separation factors decreased with respect to increasing column temperature. Possible working temperature of diamide phase was between $130-190^{\circ}C$ for N-(N-benzoyl-L-phenylalanyl)-anilide and $130-180^{\circ}C$ for other three diamide phases. The differential Gibb's free energy (${\Delta}{\Delta}G$) of enantiomers was in the range of -100--180 cal/mol for ten amino acids and -40--60 cal/mol for alanine and aspartic acid.
목차
등록된 정보가 없습니다.
참고문헌 (0)
참고문헌 신청함께 읽어보면 좋을 논문
논문 유사도에 따라 DBpia 가 추천하는 논문입니다. 함께 보면 좋을 연관 논문을 확인해보세요!
-
가스크로마토그라피에 의한 아미노산 광학이성체의 분리 II
약학회지
1986 .01
-
가스크로마토그라피에 의한 아미노산 광학이성체의 분리 I 광학활성 N-Benzoyl-L-Valine 유도체의 고정상으로의 응용
약학회지
1985 .01
-
아미노산 Phenylthiohydantoin 유도체를 키랄 고정상으로 한 GC에 의한 아미노산 광학 이성질체의 상호분리
약학회지
1988 .01
-
Enantiomer Separation of Chiral Drugs on HPLC Chiral Stationary Phases
대한약학회 학술대회
2002 .01
-
Chiral Separation of Aromatic Amino Acids by Capillary Electrophoresis using (+)-18-crown-6 tetracarboxylic acid and (-)-18-crown-6 tetracarboxylic acid as Chiral Selectors
대한약학회 학술대회
2003 .01
-
대두 ( 조사 ) 의 발효에 의한 Amino acid 의 변화에 관한 연구 ( Studies on the Charges in Amino acid if Soybean ( irradiated ) during Fermentation )
환경위생공학
1987 .01
-
토끼간에서의 아미노산 이용에 관한 실험적 연구
Annals of Surgical Treatment and Research
1990 .11
-
HPLC Resolution of Enantiomers Using Polysaccharide Derivatives as Chiral Stationay Phases
대한약학회 학술대회
2002 .01
-
Amino Acid Complex의 항노화 작용
대한화장품학회지
2006 .01
-
한국 전통 간장의 숙성중 관능적 품질에 미치는 성분의 변화-아미노산성질소,아미노산 및 색도르 중심으로
한국환경보건학회지
2004 .01
-
Studies on Colon-specific prodrugs: Structural effect of amino acid on the hydrolysis of N-benzoyl-amino acid conjugate by the rat cecal contents.
대한약학회 학술대회
2002 .01
-
Chiral separation of amino acids in urine specimens from patients with inherited metabolic disorders by achiral gas chromatography
대한약학회 학술대회
2003 .01
-
Chiral Recognition in Gas chromatographic Resolution of Amino -$^1H\;and^{13}C$ Nuclear magnetic resonance studies of hydrogen bonding in dinmide chiral stationary phases-
Archives of pharmacal research : a publication of the Pharmaceutical Society of Korea
1989 .01
-
Gas-chromatography에 의한 Amino산의 분석 : N-TFA-n-Butyl ester를 중심으로
약학회지
1974 .01
-
Comparison of liquid chromatographic enantiomer resolution of racemic amino compounds on chiral stationary phases of crown ether type
대한약학회 학술대회
2003 .01
-
Remarkable impact of amino acids on ginsenoside transformation from fresh ginseng to red ginseng
Journal of Ginseng Research
2020 .05
-
The uptake of basic amino acids into fibroblasts was enhanced by PCA.
대한화장품학회 학술대회
2003 .01
-
Recent Developments in Analytical and Preparative Scale Enantioseparations
대한약학회 학술대회
2002 .01
이 논문의 저자 정보
최근 본 자료
댓글(0)
0